| Literature DB >> 27264002 |
Abstract
In 1919, the search began for the factor, later called reagin, that could mediate an allergy, such as allergic asthma, in sera of allergic subjects. In 1967, the fifth class of immunoglobulins, IgE, was discovered and found to be able to carry reagin activity. This discovery has had immense importance for the understanding, diagnosis, and treatment of allergic diseases.Entities:
Keywords: Allergy; immunoglobulin; inflammation; mast cell; reagin; sensitization
Mesh:
Substances:
Year: 2016 PMID: 27264002 DOI: 10.1016/j.jaci.2016.04.004
Source DB: PubMed Journal: J Allergy Clin Immunol ISSN: 0091-6749 Impact factor: 10.793