Literature DB >> 27259205

DNA Replication-A Matter of Fidelity.

Rais A Ganai1, Erik Johansson2.   

Abstract

The fidelity of DNA replication is determined by many factors, here simplified as the contribution of the DNA polymerase (nucleotide selectivity and proofreading), mismatch repair, a balanced supply of nucleotides, and the condition of the DNA template (both in terms of sequence context and the presence of DNA lesions). This review discusses the contribution and interplay between these factors to the overall fidelity of DNA replication.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27259205     DOI： 10.1016/j.molcel.2016.05.003

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  54 in total

1.  Redox Chemistry in the Genome: Emergence of the [4Fe4S] Cofactor in Repair and Replication.

Authors:  Jacqueline K Barton; Rebekah M B Silva; Elizabeth O'Brien
Journal:  Annu Rev Biochem       Date:  2019-06-20       Impact factor: 23.643

Review 2.  Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.

Authors:  Katherine N Choe; George-Lucian Moldovan
Journal:  Mol Cell       Date:  2017-02-02       Impact factor: 17.970

3.  Determinants of Base-Pair Substitution Patterns Revealed by Whole-Genome Sequencing of DNA Mismatch Repair Defective Escherichia coli.

Authors:  Patricia L Foster; Brittany A Niccum; Ellen Popodi; Jesse P Townes; Heewook Lee; Wazim MohammedIsmail; Haixu Tang
Journal:  Genetics       Date:  2018-06-15       Impact factor: 4.562

4.  Identification of cancer driver genes based on nucleotide context.

Authors:  Felix Dietlein; Donate Weghorn; Amaro Taylor-Weiner; André Richters; Brendan Reardon; David Liu; Eric S Lander; Eliezer M Van Allen; Shamil R Sunyaev
Journal:  Nat Genet       Date:  2020-02-03       Impact factor: 38.330

5.  Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenzyme.

Authors:  Walter J Zahurancik; Zucai Suo
Journal:  J Biol Chem       Date:  2020-10-13       Impact factor: 5.157

Review 6.  Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage.

Authors:  Priyamvada Rai; Robert W Sobol
Journal:  DNA Repair (Amst)       Date:  2019-03-02

Review 7.  Beyond speciation genes: an overview of genome stability in evolution and speciation.

Authors:  Anne-Marie Dion-Côté; Daniel A Barbash
Journal:  Curr Opin Genet Dev       Date:  2017-08-19       Impact factor: 5.578

Review 8.  Targeting evolution to inhibit antibiotic resistance.

Authors:  Houra Merrikh; Rahul M Kohli
Journal:  FEBS J       Date:  2020-06-08       Impact factor: 5.542

9.  Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load.

Authors:  Hao-Dong Li; Ileana Cuevas; Musi Zhang; Changzheng Lu; Md Maksudul Alam; Yang-Xin Fu; M James You; Esra A Akbay; He Zhang; Diego H Castrillon
Journal:  J Clin Invest       Date:  2018-08-20       Impact factor: 14.808

10.  Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade.

Authors:  Melissa A Galati; Karl P Hodel; Zachary F Pursell; Uri Tabori; Miki S Gams; Sumedha Sudhaman; Taylor Bridge; Walter J Zahurancik; Nathan A Ungerleider; Vivian S Park; Ayse B Ercan; Lazar Joksimovic; Iram Siddiqui; Robert Siddaway; Melissa Edwards; Richard de Borja; Dana Elshaer; Jiil Chung; Victoria J Forster; Nuno M Nunes; Melyssa Aronson; Xia Wang; Jagadeesh Ramdas; Andrea Seeley; Tomasz Sarosiek; Gavin P Dunn; Jonathan N Byrd; Oz Mordechai; Carol Durno; Alberto Martin; Adam Shlien; Eric Bouffet; Zucai Suo; James G Jackson; Cynthia E Hawkins; Cynthia J Guidos
Journal:  Cancer Res       Date:  2020-09-16       Impact factor: 12.701
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