Literature DB >> 27252164

Viewing Extrinsic Proteotoxic Stress Through the Lens of Amyloid Cardiomyopathy.

Valerie Sapp1, Mohit Jain1, Ronglih Liao2.   

Abstract

Proteotoxicity refers to toxic stress caused by misfolded proteins of extrinsic or intrinsic origin and plays an integral role in the pathogenesis of cardiovascular diseases. Herein, we provide an overview of the current understanding of mechanisms underlying proteotoxicity and its contribution in the pathogenesis of amyloid cardiomyopathy. ©2016 Int. Union Physiol. Sci./Am. Physiol. Soc.

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Year:  2016        PMID： 27252164      PMCID： PMC6195664          DOI： 10.1152/physiol.00047.2015

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  55 in total

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2.  Familial and primary (AL) cardiac amyloidosis: echocardiographically similar diseases with distinctly different clinical outcomes.

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Journal:  Heart       Date:  1997-07       Impact factor: 5.994

3.  Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish.

Authors:  Shikha Mishra; Jian Guan; Eva Plovie; David C Seldin; Lawreen H Connors; Giampaolo Merlini; Rodney H Falk; Calum A MacRae; Ronglih Liao
Journal:  Am J Physiol Heart Circ Physiol       Date:  2013-04-26       Impact factor: 4.733

4.  New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: impact on survival outcomes.

Authors:  Giovanni Palladini; Angela Dispenzieri; Morie A Gertz; Shaji Kumar; Ashutosh Wechalekar; Philip N Hawkins; Stefan Schönland; Ute Hegenbart; Raymond Comenzo; Efstathios Kastritis; Meletios A Dimopoulos; Arnaud Jaccard; Catherine Klersy; Giampaolo Merlini
Journal:  J Clin Oncol       Date:  2012-10-22       Impact factor: 44.544

5.  Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus.

Authors:  A Lorenzo; B Razzaboni; G C Weir; B A Yankner
Journal:  Nature       Date:  1994-04-21       Impact factor: 49.962

6.  Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure.

Authors:  J Scott Pattison; Atsushi Sanbe; Alina Maloyan; Hanna Osinska; Raisa Klevitsky; Jeffrey Robbins
Journal:  Circulation       Date:  2008-05-19       Impact factor: 29.690

7.  Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells.

Authors:  W N Yang; K G Ma; X L Chen; L L Shi; G Bu; X D Hu; H Han; Y Liu; Y H Qian
Journal:  Neuroscience       Date:  2014-08-27       Impact factor: 3.590

8.  Hypertrophic effects of calcitonin gene-related peptide (CGRP) and amylin on adult mammalian ventricular cardiomyocytes.

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Journal:  J Mol Cell Cardiol       Date:  1995-11       Impact factor: 5.000

9.  Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes.

Authors:  Helen P McWilliams-Koeppen; James S Foster; Nicole Hackenbrack; Marina Ramirez-Alvarado; Dallas Donohoe; Angela Williams; Sallie Macy; Craig Wooliver; Dale Wortham; Jennifer Morrell-Falvey; Carmen M Foster; Stephen J Kennel; Jonathan S Wall
Journal:  PLoS One       Date:  2015-09-22       Impact factor: 3.240

10.  Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage.

Authors:  Pallavi Manral; Natàlia Reixach
Journal:  Biosci Rep       Date:  2015-01-14       Impact factor: 3.840
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  5 in total

1.  Transthyretin Amyloid Cardiomyopathy: Impact of Transthyretin Amyloid Deposition in Myocardium on Cardiac Morphology and Function.

Authors:  Tomoya Nakano; Kenji Onoue; Chiyoko Terada; Satoshi Terasaki; Satomi Ishihara; Yukihiro Hashimoto; Yasuki Nakada; Hitoshi Nakagawa; Tomoya Ueda; Ayako Seno; Taku Nishida; Makoto Watanabe; Yoshinobu Hoshii; Kinta Hatakeyama; Yasuhiro Sakaguchi; Chiho Ohbayashi; Yoshihiko Saito
Journal:  J Pers Med       Date:  2022-05-13

2.  Untangle a Broken Heart via Janus Kinase 1.

Authors:  Chen Gao; Yibin Wang
Journal:  Circ Res       Date:  2017-09-01       Impact factor: 17.367

3.  Proteotoxicity in cardiac amyloidosis: amyloidogenic light chains affect the levels of intracellular proteins in human heart cells.

Authors:  Esther Imperlini; Massimiliano Gnecchi; Paola Rognoni; Eduard Sabidò; Maria Chiara Ciuffreda; Giovanni Palladini; Guadalupe Espadas; Francesco Mattia Mancuso; Margherita Bozzola; Giuseppe Malpasso; Veronica Valentini; Giuseppina Palladini; Stefania Orrù; Giovanni Ferraro; Paolo Milani; Stefano Perlini; Francesco Salvatore; Giampaolo Merlini; Francesca Lavatelli
Journal:  Sci Rep       Date:  2017-11-15       Impact factor: 4.379

4.  Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.

Authors:  Paolo Swuec; Francesca Lavatelli; Masayoshi Tasaki; Cristina Paissoni; Paola Rognoni; Martina Maritan; Francesca Brambilla; Paolo Milani; Pierluigi Mauri; Carlo Camilloni; Giovanni Palladini; Giampaolo Merlini; Stefano Ricagno; Martino Bolognesi
Journal:  Nat Commun       Date:  2019-03-20       Impact factor: 14.919

5.  Cu(II) Binding Increases the Soluble Toxicity of Amyloidogenic Light Chains.

Authors:  Rosaria Russo; Margherita Romeo; Tim Schulte; Martina Maritan; Luca Oberti; Maria Monica Barzago; Alberto Barbiroli; Carlo Pappone; Luigi Anastasia; Giovanni Palladini; Luisa Diomede; Stefano Ricagno
Journal:  Int J Mol Sci       Date:  2022-01-16       Impact factor: 5.923
  5 in total

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