Literature DB >> 27250619

Osteochondritis dissecans of the medial femoral condyle : New cell-free scaffold as a treatment option.

N Stadler1, K Trieb2.   

Abstract

There is no gold standard in treating osteochondral lesions, which is why the treatment remains very challenging. Osteochondral defects can occur in any joint, but the most common locations are the knee and the ankle. Trauma, repeated microtrauma, avascular necrosis and osteochondritis dissecans (a special type of avascular necrosis) are blamed for the cartilage damage and the damage of adjacent subchondral bone. The self-healing ability of the cartilage is unfortunately very poor; thus, it is necessary to develop new methods of cartilage repair. Unfortunately, few data and long-term survival rates for these new scaffolds are available. We report a case of osteochondritis dissecans treated with a new cell-free scaffold MaioRegen® (Fin-Ceramica Faenza Spa, Faenza, Italy).

Entities:  

Keywords:  Cartilage; Cell-free scaffold; Knee; Osteochondritis dissecans; Regeneration

Mesh:

Substances:

Year:  2016        PMID: 27250619     DOI: 10.1007/s00132-016-3267-4

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  12 in total

Review 1.  Surgical treatment for early osteoarthritis. Part I: cartilage repair procedures.

Authors:  A H Gomoll; G Filardo; L de Girolamo; J Espregueira-Mendes; J Esprequeira-Mendes; M Marcacci; W G Rodkey; J R Steadman; R J Steadman; S Zaffagnini; E Kon
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-24       Impact factor: 4.342

2.  Early osteoarthritis.

Authors:  Elizaveta Kon; Giuseppe Filardo; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-12-29       Impact factor: 4.342

Review 3.  High tibial osteotomy versus unicompartmental knee arthroplasty for medial compartment arthrosis of the knee: a review of the literature.

Authors:  Federico Dettoni; Davide Edoardo Bonasia; Filippo Castoldi; Matteo Bruzzone; Davide Blonna; Roberto Rossi
Journal:  Iowa Orthop J       Date:  2010

4.  Tibial plateau lesions. Surface reconstruction with a biomimetic osteochondral scaffold: Results at 2 years of follow-up.

Authors:  Elizaveta Kon; Giuseppe Filardo; Giulia Venieri; Francesco Perdisa; Maurilio Marcacci
Journal:  Injury       Date:  2014-10-29       Impact factor: 2.586

5.  Novel nano-composite multilayered biomaterial for osteochondral regeneration: a pilot clinical trial.

Authors:  Elizaveta Kon; Marco Delcogliano; Giuseppe Filardo; Maurizio Busacca; Alessandro Di Martino; Maurilio Marcacci
Journal:  Am J Sports Med       Date:  2011-02-10       Impact factor: 6.202

6.  Treatment of osteochondral lesions in the knee using a cell-free scaffold.

Authors:  P Verdonk; A Dhollander; K F Almqvist; R Verdonk; J Victor
Journal:  Bone Joint J       Date:  2015-03       Impact factor: 5.082

7.  Two- to 9-year outcome after autologous chondrocyte transplantation of the knee.

Authors:  L Peterson; T Minas; M Brittberg; A Nilsson; E Sjögren-Jansson; A Lindahl
Journal:  Clin Orthop Relat Res       Date:  2000-05       Impact factor: 4.176

8.  Interspecies differences in bone composition, density, and quality: potential implications for in vivo bone research.

Authors:  J Aerssens; S Boonen; G Lowet; J Dequeker
Journal:  Endocrinology       Date:  1998-02       Impact factor: 4.736

9.  Poor osteochondral repair by a biomimetic collagen scaffold: 1- to 3-year clinical and radiological follow-up.

Authors:  Bjørn Borsøe Christensen; Casper Bindzus Foldager; Jonas Jensen; Niels Christian Jensen; Martin Lind
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-02-18       Impact factor: 4.342

10.  Orderly osteochondral regeneration in a sheep model using a novel nano-composite multilayered biomaterial.

Authors:  Elizaveta Kon; Marco Delcogliano; Giuseppe Filardo; Milena Fini; Gianluca Giavaresi; Silvia Francioli; Ivan Martin; Daniele Pressato; Elena Arcangeli; Rodolfo Quarto; Monica Sandri; Maurillo Marcacci
Journal:  J Orthop Res       Date:  2010-01       Impact factor: 3.494

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  2 in total

1.  Preparation of a biphase composite scaffold and its application in tissue engineering for femoral osteochondral defects in rabbits.

Authors:  Shi-Qiang Ruan; Ling Yan; Jiang Deng; Wen-Liang Huang; Dian-Ming Jiang
Journal:  Int Orthop       Date:  2017-06-14       Impact factor: 3.075

2.  Clinical and Biological Signature of Osteochondritis Dissecans in a Cross-Sectional Study.

Authors:  Elena Gabusi; Cristina Manferdini; Francesca Paolella; Laura Gambari; Elizaveta Kon; Giuseppe Filardo; Erminia Mariani; Gina Lisignoli
Journal:  Biomed Res Int       Date:  2018-05-28       Impact factor: 3.411

  2 in total

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