| Literature DB >> 27235205 |
Abstract
Total serum/plasma bilirubin (TB), the biochemical measure currently used to evaluate and manage hyperbilirubinemia, is not a useful predictor of bilirubin-induced neurotoxicity in premature infants. Altered bilirubin-albumin binding in premature infants limits the usefulness of TB in premature infants. In this article, bilirubin-albumin binding, a modifying factor for bilirubin-induced neurotoxicity, in premature infants is reviewed.Entities:
Keywords: Bilirubin-induced neurotoxicity; Bilirubin:albumin molar ratio; Bilirubin–albumin binding affinity; Total serum bilirubin; Unbound bilirubin
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Year: 2016 PMID: 27235205 PMCID: PMC4884605 DOI: 10.1016/j.clp.2016.01.003
Source DB: PubMed Journal: Clin Perinatol ISSN: 0095-5108 Impact factor: 3.430