Literature DB >> 27230530

Replicating repetitive DNA.

Silvia Tognetti1,2,3, Christian Speck1,2.   

Abstract

The function and regulation of repetitive DNA, the 'dark matter' of the genome, is still only rudimentarily understood. Now a study investigating DNA replication of repetitive centromeric chromosome segments has started to expose a fascinating replication program that involves suppression of ATR signalling, in particular during replication stress.

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Year:  2016        PMID： 27230530     DOI： 10.1038/ncb3367

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  13 in total

Review 1.  Eukaryotic chromosome DNA replication: where, when, and how?

Authors:  Hisao Masai; Seiji Matsumoto; Zhiying You; Naoko Yoshizawa-Sugata; Masako Oda
Journal:  Annu Rev Biochem       Date:  2010       Impact factor: 23.643

2.  ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

Authors:  Luis Ignacio Toledo; Matthias Altmeyer; Maj-Britt Rask; Claudia Lukas; Dorthe Helena Larsen; Lou Klitgaard Povlsen; Simon Bekker-Jensen; Niels Mailand; Jiri Bartek; Jiri Lukas
Journal:  Cell       Date:  2013-11-21       Impact factor: 41.582

Review 3.  ATR: an essential regulator of genome integrity.

Authors:  Karlene A Cimprich; David Cortez
Journal:  Nat Rev Mol Cell Biol       Date:  2008-07-02       Impact factor: 94.444

Review 4.  Repeat DNA in genome organization and stability.

Authors:  Jan Padeken; Peter Zeller; Susan M Gasser
Journal:  Curr Opin Genet Dev       Date:  2015-04-29       Impact factor: 5.578

Review 5.  The CINs of the centromere.

Authors:  Susan L Forsburg
Journal:  Biochem Soc Trans       Date:  2013-12       Impact factor: 5.407

Review 6.  How shelterin protects mammalian telomeres.

Authors:  Wilhelm Palm; Titia de Lange
Journal:  Annu Rev Genet       Date:  2008       Impact factor: 16.830

7.  The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis.

Authors:  Joanna E Haye; Alison E Gammie
Journal:  PLoS Genet       Date:  2015-12-18       Impact factor: 5.917

8.  Replication fork regression in repetitive DNAs.

Authors:  Nicole Fouché; Sezgin Ozgür; Debasmita Roy; Jack D Griffith
Journal:  Nucleic Acids Res       Date:  2006-10-28       Impact factor: 16.971

9.  Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression.

Authors:  Antoine Aze; Vincenzo Sannino; Paolo Soffientini; Angela Bachi; Vincenzo Costanzo
Journal:  Nat Cell Biol       Date:  2016-04-25       Impact factor: 28.824

Review 10.  Switch on the engine: how the eukaryotic replicative helicase MCM2-7 becomes activated.

Authors:  Silvia Tognetti; Alberto Riera; Christian Speck
Journal:  Chromosoma       Date:  2014-10-12       Impact factor: 4.316
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