Literature DB >> 27229746

Life-threatening angio-oedema after the first dose of an ACE inhibitor-not an anaphylactic reaction.

Troels Krogh Nielsen1, Anette Bygum2, Eva Rye Rasmussen1.   

Abstract

We present a case of a 60-year-old Caucasian woman, with no prior history of swellings, who was admitted to a hospital due to life-threatening angio-oedema. She had, the previous day, been prescribed an ACE inhibitor for her essential hypertension. She had taken one tablet at night-time, and awoke in the morning with a swollen face progressing to involve the tongue and throat within a few hours. On arrival at her doctor's office, her voice had altered. Corticosteroids and antihistamine were administered while awaiting an ambulance. Arriving at the emergency department, she had dyspnoea due to increasingly severe angio-oedema of the upper airways. Neither adrenaline inhalations, intravenously administrated corticosteroids, atropine nor furosemide were effective and the patient soon become bradycardic. A tracheotomy was performed and the patient was placed on a ventilator. She eventually made a full recovery. It was concluded that she had suffered from life-threatening angio-oedema due to her new medication. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 27229746      PMCID: PMC4885522          DOI: 10.1136/bcr-2016-214364

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  17 in total

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4.  Ecallantide for the acute treatment of angiotensin-converting enzyme inhibitor-induced angioedema: a multicenter, randomized, controlled trial.

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Authors:  Guillaume Pare; Michiaki Kubo; James B Byrd; Catherine A McCarty; Alencia Woodard-Grice; Koon K Teo; Sonia S Anand; Rebecca L Zuvich; Yuki Bradford; Stephanie Ross; Yusuke Nakamura; Marylyn Ritchie; Nancy J Brown
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6.  Plasma bradykinin in angio-oedema.

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7.  Angioedema from angiotensin-converting enzyme (ACE) inhibitor treated with complement 1 (C1) inhibitor concentrate.

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8.  Angiotensin converting enzyme inhibitor-related angioedema: onset, presentation, and management.

Authors:  Norman J Chan; Ahmed M S Soliman
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9.  The role of ace gene polymorphism in the development of angioedema secondary to angiotensin converting enzyme inhibitors and angiotensin II receptor blockers.

Authors:  M Gulec; Z Caliskaner; Y Tunca; S Ozturk; E Bozoglu; D Gul; F Erel; O Kartal; M Karaayvaz
Journal:  Allergol Immunopathol (Madr)       Date:  2008 May-Jun       Impact factor: 1.667

10.  Life-threatening ACE inhibitor-induced angioedema after eleven years on lisinopril.

Authors:  Johanna L Norman; Whitney L Holmes; William A Bell; Shannon W Finks
Journal:  J Pharm Pract       Date:  2012-11-25
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  1 in total

1.  Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches.

Authors:  Haivin Aziz Ali; Anne Fog Lomholt; Seyed Hamidreza Mahmoudpour; Thorbjørn Hermanrud; Anette Bygum; Christian von Buchwald; Marianne Antonius Jakobsen; Eva Rye Rasmussen
Journal:  PLoS One       Date:  2019-11-11       Impact factor: 3.240

  1 in total

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