Literature DB >> 27221

Intramembraneous localization of rat liver microsomal hexose-6-phosphate dehydrogenase and membrane permeability to its substrates.

T Takahashi, S H Hori.   

Abstract

A method for purifying hexose-6-phosphate dehydrogenase (beta-D-glucose: NAD(P) -oxidoreductase, EC 1.1.1.47) from rat liver microsomes is described. The purified enzyme was shown to be homogeneous by sodium dodecyl sulfate (SDS)-polyacrylamide electrophoresis. It is shown that the enzyme is bound to the inner surface of microsomal membranes, and that glucose 6-phosphate, but not NADP, penetrates almost freely into the membranes at 37 degrees C.

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Year:  1978        PMID: 27221     DOI: 10.1016/0005-2744(78)90163-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  12 in total

1.  The levels of nicotinamide nucleotides in liver microsomes and their possible significance to the function of hexose phosphate dehydrogenase.

Authors:  C Bublitz; C A Lawler
Journal:  Biochem J       Date:  1987-07-01       Impact factor: 3.857

2.  Affinity chromatography of glucose dehydrogenase.

Authors:  W R Carper; W C Groutas; D B Coffin
Journal:  Experientia       Date:  1988-01-15

3.  Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4.

Authors:  Netanya Y Spencer; Ziying Yan; Ryan L Boudreau; Yulong Zhang; Meihui Luo; Qiang Li; Xin Tian; Ajay M Shah; Robin L Davisson; Beverly Davidson; Botond Banfi; John F Engelhardt
Journal:  J Biol Chem       Date:  2011-01-06       Impact factor: 5.157

4.  In situ kinetic parameters of glucose-6-phosphate dehydrogenase and phosphogluconate dehydrogenase in different areas of the rat liver acinus.

Authors:  G N Jonges; C J Van Noorden
Journal:  Histochem J       Date:  1989 Sep-Oct

Review 5.  The glucose-6-phosphatase system.

Authors:  Emile van Schaftingen; Isabelle Gerin
Journal:  Biochem J       Date:  2002-03-15       Impact factor: 3.857

6.  Characterization studies of glucose dehydrogenase.

Authors:  W R Carper; D P Campbell; S W Morrical; R E Thompson
Journal:  Experientia       Date:  1983-11-15

7.  The activation of glucose dehydrogenase by p-chloromercuribenzoate.

Authors:  C Bublitz; C A Lawler
Journal:  Mol Cell Biochem       Date:  1989-04-11       Impact factor: 3.396

8.  Evidence that adrenal hexose-6-phosphate dehydrogenase can effect microsomal P450 cytochrome steroidogenic enzymes.

Authors:  Christy A Foster; Gail J Mick; Xudong Wang; Kenneth McCormick
Journal:  Biochim Biophys Acta       Date:  2013-05-09

9.  A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic.

Authors:  M Veiga-da-Cunha; I Gerin; Y T Chen; T de Barsy; P de Lonlay; C Dionisi-Vici; C D Fenske; P J Lee; J V Leonard; I Maire; A McConkie-Rosell; S Schweitzer; M Vikkula; E Van Schaftingen
Journal:  Am J Hum Genet       Date:  1998-10       Impact factor: 11.025

10.  Isolation and the complete amino acid sequence of lumenal endoplasmic reticulum glucose-6-phosphate dehydrogenase.

Authors:  J Ozols
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-01       Impact factor: 11.205

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