Literature DB >> 27217681

Giant Cell Tumor Bone in an Elderly Male- an Unusual Case Misdiagnosed on MRI as a Malignant Sarcoma.

Mukta Pujani1, Shalini Bahadur1, Zeeba S Jairajpuri1, Sujata Jetley1, Javed Jameel2.   

Abstract

Giant cell tumor (GCT) of the bone is a benign locally aggressive neoplasm which accounts for 3-8 % of all primary bone tumors. 60-70 % of the patients with giant cell tumor of the bone occur in the age group of 20-40 years. Patients older than 55 years of age very rarely develop GCT. Although many case series have been published on giant cell tumor of the bone, even on extensive search of literature, we found only a single series of 10 cases focusing exclusively on giant cell tumors in elderly. They observed that there was no difference in behavior of GCT in elderly and younger patients in terms of location of tumor, radiographic features and clinical course. We present a case of GCT of tibia in an elderly male without any evidence of malignant transformation or dedifferentiation, despite magnetic resonance imaging revealing features of a malignant lesion.

Entities:  

Keywords:  Bone tumor; Elderly; Giant cell tumor

Year:  2015        PMID: 27217681      PMCID: PMC4856668          DOI: 10.1007/s13193-015-0408-x

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  9 in total

1.  Analysis of chromosomal imbalances in an elderly woman with a giant cell tumour.

Authors:  Juan Luis García; Cristina Robledo; E Lumbreras; Teresa Flores; Luis Ramos; Jesús M Hernández
Journal:  Virchows Arch       Date:  2005-10-12       Impact factor: 4.064

2.  Osteoclast-rich undifferentiated carcinomas of the urinary tract.

Authors:  Dilek Baydar; Mahul B Amin; Jonathan I Epstein
Journal:  Mod Pathol       Date:  2006-02       Impact factor: 7.842

3.  Giant cell tumor of bone in elderly patients: a study of ten patients.

Authors:  Edward F McCarthy; Kristy L Weber
Journal:  Iowa Orthop J       Date:  2009

4.  Curettage and radiotherapy of giant cell tumour of the sacrum: a case report with a 10-year follow-up.

Authors:  M Kanamori; K Ohmori
Journal:  J Orthop Surg (Hong Kong)       Date:  2005-08       Impact factor: 1.118

5.  Imaging of giant cell tumor of bone.

Authors:  Shaligram Purohit; Dinshaw N Pardiwala
Journal:  Indian J Orthop       Date:  2007-04       Impact factor: 1.251

6.  Giant cell tumor of the thumb metacarpal in an elderly patient: a case report.

Authors:  D C Henard
Journal:  J Hand Surg Am       Date:  1984-05       Impact factor: 2.230

7.  Giant-cell tumor of bone.

Authors:  M Campanacci; N Baldini; S Boriani; A Sudanese
Journal:  J Bone Joint Surg Am       Date:  1987-01       Impact factor: 5.284

Review 8.  Syncytial giant cell component. Review of 55 renal cell carcinomas.

Authors:  F Berzal Cantalejo; V Sabater Marco; S Alonso Hernández; R Jiménez Peña; M A Martorell Cebollada
Journal:  Histol Histopathol       Date:  2004-01       Impact factor: 2.303

9.  Giant cell tumor of bone: treatment and outcome of 214 cases.

Authors:  Maurice Balke; Laura Schremper; Carsten Gebert; Helmut Ahrens; Arne Streitbuerger; Gabriele Koehler; Jendrik Hardes; Georg Gosheger
Journal:  J Cancer Res Clin Oncol       Date:  2008-03-06       Impact factor: 4.553

  9 in total
  4 in total

1.  Giant Cell Tumor of Clavicle in an Elderly: Rare Presentation of a Common Tumor with Review of Literature; 1980-2020.

Authors:  Neha Garg; Nadeem Tanveer; Shilpi More; Shivangi Chauhan
Journal:  J Microsc Ultrastruct       Date:  2021-09-08

2.  An Unusual and Complicated Course of a Giant Cell Tumor of the Capitate Bone.

Authors:  Ingo Schmidt
Journal:  Case Rep Orthop       Date:  2016-10-25

3.  Diagnosis of bone giant cell tumor in elderly patient: A case report of an unusual case.

Authors:  Paulus Raharjo; Rosy Setiawati
Journal:  Ann Med Surg (Lond)       Date:  2022-06-29

4.  Expression of MMP-2 and TIMP-3 with incidence and prognosis of giant-cell tumor of the bone.

Authors:  Zhendong Liu; Yuxin Ren; Fuqiang Zhu
Journal:  Oncol Lett       Date:  2018-05-10       Impact factor: 2.967

  4 in total

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