| Literature DB >> 27216056 |
Katihuska Paredes1, Javier Capilla2, Emilio Mayayo3, Josep Guarro1.
Abstract
Different inocula of Trichoderma longibrachiatum were tested in a murine model, and only the highest one (1 × 10(7) CFU/animal) killed all of the mice at day 15 postinfection, with spleen and liver the most affected organs. The efficacies of amphotericin B deoxycholate, liposomal amphotericin B, voriconazole, and micafungin were evaluated in the same model, with very poor results. Our study demonstrated the low virulence but high resistance to antifungal compounds of this fungus.Entities:
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Year: 2016 PMID: 27216056 PMCID: PMC4958234 DOI: 10.1128/AAC.00373-16
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191