P Gao1, H Wang1, W X Chen1, Y N Sun1, W Zhang1, X H Pang2, X He2, J Wu1. 1. Institute for Immunization of Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China. 2. Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
Abstract
OBJECTIVE: To understand the sero-prevalence of hepatitis B in general population in Beijing and provide evidence for the prevention and control of hepatitis B. METHODS: A serological survey was conducted in general population aged >1 year selected through multistage randomized cluster sampling in Beijing from August 2013 to February 2014. The estimated sample size was 5 200. Venous blood samples were collected from them to detect five hepatitis B serological indicators. The information about the hepatitis B immunization history and risk factors of the study subjects were collected through a questionnaire survey. RESULTS: A total of 6 705 people were surveyed. The sero-positive rates of HBsAg, anti-HBs, anti-HBc and total HBV infection rate were 2.74%, 44.72%, 26.91% and 26.95% respectively. The age standardized rates were 2.73%, 44.83%, 26.84% and 26.87% respectively. As for the general population, in Beijing since the prevalence rate of hepatitis B surface antigen has decreased to 2.73%, <1% in children aged less than 5 years old, <1% in people aged less than 25 years old. CONCLUSION: The integrated prevention and control strategy of hepatitis B had a significant effect in Beijing. We should continue to strengthen the work of adult hepatitis B vaccination.
OBJECTIVE: To understand the sero-prevalence of hepatitis B in general population in Beijing and provide evidence for the prevention and control of hepatitis B. METHODS: A serological survey was conducted in general population aged >1 year selected through multistage randomized cluster sampling in Beijing from August 2013 to February 2014. The estimated sample size was 5 200. Venous blood samples were collected from them to detect five hepatitis B serological indicators. The information about the hepatitis B immunization history and risk factors of the study subjects were collected through a questionnaire survey. RESULTS: A total of 6 705 people were surveyed. The sero-positive rates of HBsAg, anti-HBs, anti-HBc and total HBV infection rate were 2.74%, 44.72%, 26.91% and 26.95% respectively. The age standardized rates were 2.73%, 44.83%, 26.84% and 26.87% respectively. As for the general population, in Beijing since the prevalence rate of hepatitis B surface antigen has decreased to 2.73%, <1% in children aged less than 5 years old, <1% in people aged less than 25 years old. CONCLUSION: The integrated prevention and control strategy of hepatitis B had a significant effect in Beijing. We should continue to strengthen the work of adult hepatitis B vaccination.