Literature DB >> 27188298

The History of the HIV/AIDS Epidemic in Africa.

Joseph Kagaayi1, David Serwadda2,3.   

Abstract

HIV testing of African immigrants in Belgium showed that HIV existed among Africans by 1983. However, the epidemic was recognized much later in most parts of sub-Saharan Africa (SSA) due to stigma and perceived fear of possible negative consequences to the countries' economies. This delay had devastating mortality, morbidity, and social consequences. In countries where earlier recognition occurred, political leadership was vital in mounting a response. The response involved establishment of AIDS control programs and research on the HIV epidemiology and candidate preventive interventions. Over time, the number of effective interventions has grown; the game changer being triple antiretroviral therapy (ART). ART has led to a rapid decline in HIV-related morbidity and mortality in addition to prevention of onward HIV transmission. Other effective interventions include safe male circumcision, pre-exposure prophylaxis, and post-exposure prophylaxis. However, since none of these is sufficient by itself, delivering a combination package of these interventions is important for ending the HIV epidemic as a public health threat.

Entities:  

Keywords:  Africa; Antiretroviral therapy; Combination prevention; HIV prevalence; History; Stigma

Mesh:

Substances:

Year:  2016        PMID: 27188298     DOI: 10.1007/s11904-016-0318-8

Source DB:  PubMed          Journal:  Curr HIV/AIDS Rep        ISSN: 1548-3568            Impact factor:   5.071


  62 in total

1.  Postexposure prophylaxis of breastfeeding HIV-exposed infants with antiretroviral drugs to age 14 weeks: updated efficacy results of the PEPI-Malawi trial.

Authors:  Taha E Taha; Qing Li; Donald R Hoover; Linda Mipando; Kondwani Nkanaunena; Michael C Thigpen; Allan Taylor; Johnstone Kumwenda; Mary Glenn Fowler; Lynne M Mofenson; Newton I Kumwenda
Journal:  J Acquir Immune Defic Syndr       Date:  2011-08-01       Impact factor: 3.731

Review 2.  Heterosexual transmission of HIV: the role of other sexually transmitted infections and behavior in its epidemiology prevention and control.

Authors:  S O Aral
Journal:  Annu Rev Public Health       Date:  1993       Impact factor: 21.981

3.  Efficacy and safety of an extended nevirapine regimen in infant children of breastfeeding mothers with HIV-1 infection for prevention of postnatal HIV-1 transmission (HPTN 046): a randomised, double-blind, placebo-controlled trial.

Authors:  Hoosen M Coovadia; Elizabeth R Brown; Mary Glenn Fowler; Tsungai Chipato; Dhayendre Moodley; Karim Manji; Philippa Musoke; Lynda Stranix-Chibanda; Vani Chetty; Wafaie Fawzi; Clemensia Nakabiito; Lindiwe Msweli; Roderick Kisenge; Laura Guay; Anthony Mwatha; Diana J Lynn; Susan H Eshleman; Paul Richardson; Kathleen George; Philip Andrew; Lynne M Mofenson; Sheryl Zwerski; Yvonne Maldonado
Journal:  Lancet       Date:  2011-12-22       Impact factor: 79.321

4.  Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.

Authors:  Michael C Thigpen; Poloko M Kebaabetswe; Lynn A Paxton; Dawn K Smith; Charles E Rose; Tebogo M Segolodi; Faith L Henderson; Sonal R Pathak; Fatma A Soud; Kata L Chillag; Rodreck Mutanhaurwa; Lovemore Ian Chirwa; Michael Kasonde; Daniel Abebe; Evans Buliva; Roman J Gvetadze; Sandra Johnson; Thom Sukalac; Vasavi T Thomas; Clyde Hart; Jeffrey A Johnson; C Kevin Malotte; Craig W Hendrix; John T Brooks
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

5.  Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.

Authors:  Jared M Baeten; Deborah Donnell; Patrick Ndase; Nelly R Mugo; James D Campbell; Jonathan Wangisi; Jordan W Tappero; Elizabeth A Bukusi; Craig R Cohen; Elly Katabira; Allan Ronald; Elioda Tumwesigye; Edwin Were; Kenneth H Fife; James Kiarie; Carey Farquhar; Grace John-Stewart; Aloysious Kakia; Josephine Odoyo; Akasiima Mucunguzi; Edith Nakku-Joloba; Rogers Twesigye; Kenneth Ngure; Cosmas Apaka; Harrison Tamooh; Fridah Gabona; Andrew Mujugira; Dana Panteleeff; Katherine K Thomas; Lara Kidoguchi; Meighan Krows; Jennifer Revall; Susan Morrison; Harald Haugen; Mira Emmanuel-Ogier; Lisa Ondrejcek; Robert W Coombs; Lisa Frenkel; Craig Hendrix; Namandjé N Bumpus; David Bangsberg; Jessica E Haberer; Wendy S Stevens; Jairam R Lingappa; Connie Celum
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

6.  Mortality associated with HIV infection in rural Rakai District, Uganda.

Authors:  N K Sewankambo; R H Gray; S Ahmad; D Serwadda; F Wabwire-Mangen; F Nalugoda; N Kiwanuka; T Lutalo; G Kigozi; C Li; M P Meehan; H Brahmbatt; M J Wawer
Journal:  AIDS       Date:  2000-10-20       Impact factor: 4.177

Review 7.  Provider-initiated HIV testing and counseling in low- and middle-income countries: a systematic review.

Authors:  Caitlin E Kennedy; Virginia A Fonner; Michael D Sweat; F Amolo Okero; Rachel Baggaley; Kevin R O'Reilly
Journal:  AIDS Behav       Date:  2013-06

8.  "They don't care what happens to us." The situation of double orphans heading households in Rakai District, Uganda.

Authors:  Nina Dalen; Ann Jacqueline Nakitende; Seggane Musisi
Journal:  BMC Public Health       Date:  2009-09-04       Impact factor: 3.295

9.  Origin of AIDS: contaminated polio vaccine theory refuted.

Authors:  Michael Worobey; Mario L Santiago; Brandon F Keele; Jean-Bosco N Ndjango; Jeffrey B Joy; Bernard L Labama; Benoît D Dhed'A; Andrew Rambaut; Paul M Sharp; George M Shaw; Beatrice H Hahn
Journal:  Nature       Date:  2004-04-22       Impact factor: 49.962

10.  Bed occupancy due to HIV/AIDS in an urban hospital medical ward in Uganda.

Authors:  G Tembo; H Friesan; G Asiimwe-Okiror; R Moser; W Naamara; N Bakyaita; J Musinguzi
Journal:  AIDS       Date:  1994-08       Impact factor: 4.177

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  8 in total

Review 1.  The global movement towards a public health approach to substance use disorders.

Authors:  Kimberly Johnson; Irina Pinchuk; Marie Isabel E Melgar; Martin Osayande Agwogie; Fernando Salazar Silva
Journal:  Ann Med       Date:  2022-12       Impact factor: 5.348

2.  Institutional Arrangements for Providing HIV and AIDS Services in Uganda: A Transaction Cost Economics Analysis.

Authors:  Sarah Khanakwa; Josue Mbonigaba
Journal:  Health Serv Insights       Date:  2022-05-09

3.  Betting on the fastest horse: Using computer simulation to design a combination HIV intervention for future projects in Maharashtra, India.

Authors:  Kelly V Ruggles; Anik R Patel; Stephen Schensul; Jean Schensul; Kimberly Nucifora; Qinlian Zhou; Kendall Bryant; R Scott Braithwaite
Journal:  PLoS One       Date:  2017-09-05       Impact factor: 3.240

Review 4.  Population Structure and Implications on the Genetic Architecture of HIV-1 Phenotypes Within Southern Africa.

Authors:  Prisca K Thami; Emile R Chimusa
Journal:  Front Genet       Date:  2019-09-27       Impact factor: 4.599

5.  Understanding COVID-19: the virus.

Authors:  Jeremy J Hoffman; Adiele E Hoffman
Journal:  Community Eye Health       Date:  2020-09-01

6.  Encountering Covid-19 and perceived stress and the role of a health climate among medical workers.

Authors:  Sammar Abbas; Hadi Al-Abrrow; Hasan Oudah Abdullah; Alhamzah Alnoor; Zeeshan Zaib Khattak; Khai Wah Khaw
Journal:  Curr Psychol       Date:  2021-01-23

7.  Women's sexual scripting in the context of universal access to antiretroviral treatment-findings from the HPTN 071 (PopART) trial in South Africa.

Authors:  Lario Viljoen; Graeme Hoddinott; Samantha Malunga; Nosivuyile Vanqa; Tembeka Mhlakwaphalwa; Arlene Marthinus; Khanyisa Mcimeli; Virginia Bond; Janet Seeley; Peter Bock; Richard Hayes; Lindsey Reynolds
Journal:  BMC Womens Health       Date:  2021-10-24       Impact factor: 2.742

8.  Age patterns of HIV incidence in eastern and southern Africa: a modelling analysis of observational population-based cohort studies.

Authors:  Kathryn A Risher; Anne Cori; Georges Reniers; Milly Marston; Clara Calvert; Amelia Crampin; Tawanda Dadirai; Albert Dube; Simon Gregson; Kobus Herbst; Tom Lutalo; Louisa Moorhouse; Baltazar Mtenga; Dorean Nabukalu; Robert Newton; Alison J Price; Malebogo Tlhajoane; Jim Todd; Keith Tomlin; Mark Urassa; Alain Vandormael; Christophe Fraser; Emma Slaymaker; Jeffrey W Eaton
Journal:  Lancet HIV       Date:  2021-07       Impact factor: 12.767

  8 in total

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