Lei Cui1, Jian-Bing Yin2, Chun-Hong Hu3, Shen-Chu Gong4, Jun-Feng Xu2, Ju-Shun Yang2. 1. Department of Radiology, First Affiliated Hospital of Soochow University, 188 Shixi Street, Suzhou, Jiangsu, PR China, 215006; Department of Radiology, Second Affiliated Hospital of Nantong University, 6 Hai'er Road, Chongchuan District, Nantong, Jiangsu, PR China, 226001. 2. Department of Radiology, Second Affiliated Hospital of Nantong University, 6 Hai'er Road, Chongchuan District, Nantong, Jiangsu, PR China, 226001. 3. Department of Radiology, First Affiliated Hospital of Soochow University, 188 Shixi Street, Suzhou, Jiangsu, PR China, 215006. Electronic address: drhuchunhong@163.com. 4. Department of Radiology, Second Affiliated Hospital of Nantong University, 6 Hai'er Road, Chongchuan District, Nantong, Jiangsu, PR China, 226001. Electronic address: gongshenchu@126.com.
Abstract
OBJECTIVE: To prospectively evaluate the inter- and intraobserver agreement of apparent diffusion coefficient (ADC) measurements in free breathing, breath-hold, and respiratory triggered diffusion-weighted imaging (DWI) of lung cancer. METHODS: Twenty-two patients with lung cancer (tumor size >2cm) underwent DWIs (3.0T) in three imaging methods. Lesion ADCs were measured twice by both of the two independent observers and compared. RESULTS: No statistical significance was found among methods, though respiratory-triggered DWI tended to have higher ADCs than breath-hold DWI. Great inter- and intraobserver agreement was shown. CONCLUSION: ADCs had good inter- and intraobserver agreement in all three DWI methods.
OBJECTIVE: To prospectively evaluate the inter- and intraobserver agreement of apparent diffusion coefficient (ADC) measurements in free breathing, breath-hold, and respiratory triggered diffusion-weighted imaging (DWI) of lung cancer. METHODS: Twenty-two patients with lung cancer (tumor size >2cm) underwent DWIs (3.0T) in three imaging methods. Lesion ADCs were measured twice by both of the two independent observers and compared. RESULTS: No statistical significance was found among methods, though respiratory-triggered DWI tended to have higher ADCs than breath-hold DWI. Great inter- and intraobserver agreement was shown. CONCLUSION: ADCs had good inter- and intraobserver agreement in all three DWI methods.
Authors: Alexander W Sauter; Bram Stieltjes; Thomas Weikert; Sergios Gatidis; Mark Wiese; Markus Klarhöfer; Damian Wild; Didier Lardinois; Jens Bremerich; Gregor Sommer Journal: Contrast Media Mol Imaging Date: 2017-12-17 Impact factor: 3.161