Literature DB >> 27182194

Strategies and Methods for the Synthesis of Anticancer Natural Product Neopeltolide and its Analogs.

Yu Bai1, Mingji Dai1.   

Abstract

Neopeltolide, isolated in 2007, with its novel structural features and potent anti cancer cell proliferation activity, has attracted a tremendous amount of synthetic efforts. This review briefly and chronologically summarizes each of the synthesis with the main focus on the strategies and methodologies for the construction of its cis-tetrahydropyran-containing macrolactone core.

Entities:  

Keywords:  anticancer; carbonylation; macrolactone; neopeltolide; palladium; tetrahydropyran

Year:  2015        PMID： 27182194      PMCID： PMC4863658          DOI： 10.2174/1385272819666150119225149

Source DB:  PubMed          Journal:  Curr Org Chem        ISSN： 1385-2728            Impact factor:   2.180


  43 in total

1.  Concise formal synthesis of (+)-neopeltolide.

Authors:  Zhen Yang; Bingbin Zhang; Gaoyuan Zhao; Juan Yang; Xingang Xie; Xuegong She
Journal:  Org Lett       Date:  2011-10-13       Impact factor: 6.005

2.  Total synthesis of (+)-neopeltolide.

Authors:  Haruhiko Fuwa; Shinya Naito; Tomomi Goto; Makoto Sasaki
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

3.  Formal total synthesis of (+)-neopeltolide.

Authors:  Sudhakar Athe; Balla Chandrasekhar; Saumya Roy; Tapan Kumar Pradhan; Subhash Ghosh
Journal:  J Org Chem       Date:  2012-10-15       Impact factor: 4.354

4.  Total synthesis and structure-activity investigation of the marine natural product neopeltolide.

Authors:  Daniel W Custar; Thomas P Zabawa; John Hines; Craig M Crews; Karl A Scheidt
Journal:  J Am Chem Soc       Date:  2009-09-02       Impact factor: 15.419

5.  Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae.

Authors:  Amy E Wright; Julianne Cook Botelho; Esther Guzmán; Dedra Harmody; Patricia Linley; Peter J McCarthy; Tara P Pitts; Shirley A Pomponi; John K Reed
Journal:  J Nat Prod       Date:  2007-02-20       Impact factor: 4.050

6.  Synthesis and biological evaluation of neopeltolide and analogs.

Authors:  Yubo Cui; Raghavan Balachandran; Billy W Day; Paul E Floreancig
Journal:  J Org Chem       Date:  2012-02-22       Impact factor: 4.354

7.  Concise enantioselective total synthesis of neopeltolide macrolactone highlighted by ether transfer.

Authors:  Rendy Kartika; Thomas R Gruffi; Richard E Taylor
Journal:  Org Lett       Date:  2008-10-15       Impact factor: 6.005

8.  Total synthesis and structural revision of the marine macrolide neopeltolide.

Authors:  Daniel W Custar; Thomas P Zabawa; Karl A Scheidt
Journal:  J Am Chem Soc       Date:  2008-01-23       Impact factor: 15.419

9.  Oxidative carbocation formation in macrocycles: synthesis of the neopeltolide macrocycle.

Authors:  Wangyang Tu; Paul E Floreancig
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

10.  Total synthesis and biological activity of neopeltolide and analogues.

Authors:  Viktor V Vintonyak; Brigitte Kunze; Florenz Sasse; Martin E Maier
Journal:  Chemistry       Date:  2008       Impact factor: 5.236
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  3 in total

1.  Total Synthesis of (-)-Spinosyn A via Carbonylative Macrolactonization.

Authors:  Yu Bai; Xingyu Shen; Yong Li; Mingji Dai
Journal:  J Am Chem Soc       Date:  2016-08-17       Impact factor: 15.419

2.  Diastereo- and Enantioselective Access to Stereotriads through a Flexible Coupling of Substituted Aldehydes and Alkenes.

Authors:  Jing Li; Alexander Preinfalk; Nuno Maulide
Journal:  Angew Chem Int Ed Engl       Date:  2019-03-27       Impact factor: 15.336

3.  A Synthetic Analogue of Neopeltolide, 8,9-Dehydroneopeltolide, Is a Potent Anti-Austerity Agent against Starved Tumor Cells.

Authors:  Haruhiko Fuwa; Mizuho Sato
Journal:  Mar Drugs       Date:  2017-10-20       Impact factor: 5.118
  3 in total

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