Literature DB >> 27175315

Small Vestibular Schwannomas: Does Surgery Remain a Viable Treatment Option?

Amjad N Anaizi1, Vincent V DiNapoli2, Myles Pensak3, Philip V Theodosopoulos4.   

Abstract

Background Surgery for small vestibular schwannomas (Koos grade I and II) has been increasingly rejected as the optimal primary treatment, instead favoring radiosurgery and observation that offer lower morbidity and potentially equal efficacy. Our study assesses the outcomes of contemporary surgical strategies including tumor control, functional preservation, and implications of pathologic findings. Design Retrospective review. Setting/Participants Eighty consecutive patients (45 women, 35 men; mean: 47 years of age). Main Outcomes Measures Approaches included retrosigmoid approach (52%), translabyrinthine (40%), and middle fossa (8%). Operated on by the same surgical team, we analyzed presentation, radiographic imaging, surgical data, and outcomes. Results At last follow-up (mean: 34 months), 95% had good facial nerve function (House-Brackmann grade I or II); 36% who presented with serviceable hearing retained it; and 93% who presented with vestibular dysfunction reported resolution. Pathology identified two grade I meningiomas. Conclusions As one of the largest contemporary surgical series of small vestibular schwannomas, we discuss some nuances to help refine treatment algorithms. Although observation and radiosurgery have established roles, our results reinforce microsurgery as a viable, safe option for a subgroup of patients.

Entities:  

Keywords:  acoustic neuroma; disequilibrium; dizziness; facial nerve function; hearing preservation; outcomes; quality of life; vestibular dysfunction

Year:  2015        PMID: 27175315      PMCID: PMC4862868          DOI: 10.1055/s-0035-1564591

Source DB:  PubMed          Journal:  J Neurol Surg B Skull Base        ISSN: 2193-634X


  40 in total

Review 1.  Hearing preservation in the removal of intracanalicular acoustic neuromas via the retrosigmoid approach.

Authors:  D W Rowed; J M Nedzelski
Journal:  J Neurosurg       Date:  1997-03       Impact factor: 5.115

2.  Hearing preservation in acoustic neuroma surgery: middle fossa versus retrosigmoid approach.

Authors:  H Staecker; J B Nadol; R Ojeman; S Ronner; M J McKenna
Journal:  Am J Otol       Date:  2000-05

3.  Conservative management or gamma knife radiosurgery for vestibular schwannoma: tumor growth, symptoms, and quality of life.

Authors:  Cathrine Nansdal Breivik; Roy Miodini Nilsen; Erling Myrseth; Paal Henning Pedersen; Jobin K Varughese; Aqeel Asghar Chaudhry; Morten Lund-Johansen
Journal:  Neurosurgery       Date:  2013-07       Impact factor: 4.654

4.  Facial nerve function after vestibular schwannoma surgery.

Authors:  Maurizio Falcioni; Paolo Fois; Abdelkader Taibah; Mario Sanna
Journal:  J Neurosurg       Date:  2011-06-17       Impact factor: 5.115

5.  Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: the Greek experience.

Authors:  Maria-Aggeliki Kalogeridi; Paraskevi Georgolopoulou; Vassilis Kouloulias; John Kouvaris; George Pissakas
Journal:  J Cancer Res Ther       Date:  2009 Jan-Mar       Impact factor: 1.805

6.  Hearing preservation after intracanalicular vestibular schwannoma radiosurgery.

Authors:  Ajay Niranjan; David Mathieu; John C Flickinger; Douglas Kondziolka; L Dade Lunsford
Journal:  Neurosurgery       Date:  2008-12       Impact factor: 4.654

7.  Preservation of hearing and facial nerve function in resection of acoustic neuroma.

Authors:  J B Nadol; C M Chiong; R G Ojemann; M J McKenna; R L Martuza; W W Montgomery; R A Levine; S F Ronner; R J Glynn
Journal:  Laryngoscope       Date:  1992-10       Impact factor: 3.325

8.  Small vestibular schwannomas with no hearing: comparison of functional outcomes in stereotactic radiosurgery and microsurgery.

Authors:  Daniel H Coelho; J Thomas Roland; Stephen A Rush; Ashwatha Narayana; Eric St Clair; Wayne Chung; John G Golfinos
Journal:  Laryngoscope       Date:  2008-11       Impact factor: 3.325

9.  Gamma knife radiosurgery for vestibular schwannomas.

Authors:  Seiji Fukuoka; Masami Takanashi; Atsufumi Hojyo; Masanori Konishi; Chiharu Tanaka; Hirohiko Nakamura
Journal:  Prog Neurol Surg       Date:  2009

10.  Long-term outcome of stereotactic radiosurgery (SRS) in patients with acoustic neuromas.

Authors:  Stephanie E Combs; Christoph Thilmann; Jürgen Debus; Daniela Schulz-Ertner
Journal:  Int J Radiat Oncol Biol Phys       Date:  2006-02-07       Impact factor: 7.038

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  2 in total

1.  Fractionated vs. single-fraction stereotactic radiotherapy in patients with vestibular schwannoma : Hearing preservation and patients' self-reported outcome based on an established questionnaire.

Authors:  Kerstin A Kessel; Hanna Fischer; Marco M E Vogel; Markus Oechsner; Henning Bier; Bernhard Meyer; Stephanie E Combs
Journal:  Strahlenther Onkol       Date:  2016-11-01       Impact factor: 3.621

2.  Gamma Knife Radiosurgery for Large Vestibular Schwannoma More Than 10 cm 3 : A Single-Center Indian Study.

Authors:  Ujwal Yeole; A R Prabhuraj; Arimappamagan Arivazhagan; K V L Narasingarao; Vikas Vazhayil; Dhananjaya Bhat; Dwarakanath Srinivas; Bhanumathi Govindswamy; Somanna Sampath
Journal:  J Neurol Surg B Skull Base       Date:  2021-05-23
  2 in total

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