Literature DB >> 27175263

Targeting leukemia stem cells with HDAC inhibitors and modulators of the DNA damage response.

S Grant1.   

Abstract

Entities:  

Keywords:  DNA damage response; Histone deacetylase inhibitors; MLN4924; NAE inhibitors; Wee1; leukemia stem cells; leukemia-initiating cells

Year:  2014        PMID： 27175263      PMCID： PMC4851282          DOI： 10.1038/leusup.2014.8

Source DB:  PubMed          Journal:  Leuk Suppl        ISSN： 2044-5210


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  12 in total

Review 1.  Acetylation and deacetylation of non-histone proteins.

Authors:  Michele A Glozak; Nilanjan Sengupta; Xiaohong Zhang; Edward Seto
Journal:  Gene       Date:  2005-11-11       Impact factor: 3.688

Review 2.  Anticancer activities of histone deacetylase inhibitors.

Authors:  Jessica E Bolden; Melissa J Peart; Ricky W Johnstone
Journal:  Nat Rev Drug Discov       Date:  2006-09       Impact factor: 84.694

Review 3.  Regulation of DNA repair throughout the cell cycle.

Authors:  Dana Branzei; Marco Foiani
Journal:  Nat Rev Mol Cell Biol       Date:  2008-02-20       Impact factor: 94.444

4.  Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.

Authors:  Bin Zhang; Adam C Strauss; Su Chu; Min Li; Yinwei Ho; Keh-Dong Shiang; David S Snyder; Claudia S Huettner; Leonard Shultz; Tessa Holyoake; Ravi Bhatia
Journal:  Cancer Cell       Date:  2010-05-18       Impact factor: 31.743

5.  Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis?

Authors:  Terry J Gaymes; Rose Ann Padua; Marika Pla; Stephen Orr; Nader Omidvar; Christine Chomienne; Ghulam J Mufti; Feyruz V Rassool
Journal:  Mol Cancer Res       Date:  2006-08       Impact factor: 5.852

6.  Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924.

Authors:  Jonathan L Blank; Xiaozhen J Liu; Katherine Cosmopoulos; David C Bouck; Khristofer Garcia; Hugues Bernard; Olga Tayber; Greg Hather; Ray Liu; Usha Narayanan; Michael A Milhollen; Eric S Lightcap
Journal:  Cancer Res       Date:  2012-10-24       Impact factor: 12.701

7.  Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors.

Authors:  Ju-Hee Lee; Megan L Choy; Lang Ngo; Gisela Venta-Perez; Paul A Marks
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-21       Impact factor: 11.205

8.  Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia.

Authors:  Ronan T Swords; Kevin R Kelly; Peter G Smith; James J Garnsey; Devalingam Mahalingam; Ernest Medina; Kelli Oberheu; Swaminathan Padmanabhan; Michael O'Dwyer; Steffan T Nawrocki; Francis J Giles; Jennifer S Carew
Journal:  Blood       Date:  2010-03-04       Impact factor: 22.113

9.  The novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibitors by targeting the intra-S checkpoint and DNA replication and repair.

Authors:  Yun Dai; Shuang Chen; Maciej Kmieciak; Liang Zhou; Hui Lin; Xin-Yan Pei; Steven Grant
Journal:  Mol Cancer Ther       Date:  2013-03-27       Impact factor: 6.261

Review 10.  HDAC inhibitors: roles of DNA damage and repair.

Authors:  Carine Robert; Feyruz V Rassool
Journal:  Adv Cancer Res       Date:  2012       Impact factor: 6.242
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  1 in total

1.  Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cells.

Authors:  Yi Liao; Xiaojia Niu; Bailing Chen; Holly Edwards; Liping Xu; Chengzhi Xie; Hai Lin; Lisa Polin; Jeffrey W Taub; Yubin Ge; Zhihui Qin
Journal:  J Med Chem       Date:  2016-08-24       Impact factor: 7.446
  1 in total

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