Cesar M Salinas-La Rosa1. 1. Department of Anatomical Pathology, St Vincent's Hospital, Melbourne. Vic., Australia.
Abstract
PURPOSE OF THE STUDY: To describe the rare occurrence of a paraganglioma in the orbit and how to triage for genetic testing and assess the prognosis with succinate dehydrogenase subunit B (SDHB) immunohistochemical staining. METHOD: Case report. PROCEDURES: A 47-year-old 'healthy' male presented with painless exophthalmos and diplopia secondary to an infraorbital tumour mass. RESULTS: The orbital biopsy was diagnosed as paraganglioma with positive staining with SDHB. CONCLUSION: The rarity of an orbital paraganglioma was followed by the clinical search for a possible occult extraorbital primary paraganglioma. SDHB staining helped in the triage for genetic testing and gave an idea about the prognosis for this tumour.
PURPOSE OF THE STUDY: To describe the rare occurrence of a paraganglioma in the orbit and how to triage for genetic testing and assess the prognosis with succinate dehydrogenase subunit B (SDHB) immunohistochemical staining. METHOD: Case report. PROCEDURES: A 47-year-old 'healthy' male presented with painless exophthalmos and diplopia secondary to an infraorbital tumour mass. RESULTS: The orbital biopsy was diagnosed as paraganglioma with positive staining with SDHB. CONCLUSION: The rarity of an orbital paraganglioma was followed by the clinical search for a possible occult extraorbital primary paraganglioma. SDHB staining helped in the triage for genetic testing and gave an idea about the prognosis for this tumour.
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