Literature DB >> 25216041

Regression of a paraganglioma tumor of the orbit.

Robert H Hill1, Sean M Platt, Thomas A Bersani, Ann Barker-Griffith, Kenneth B Strumpf.   

Abstract

PURPOSE: To describe a clinical case of an orbital paraganglioma that displayed regression after biopsy alone.
METHODS: Case report.
RESULTS: A 75-year-old female was examined for a right orbital tumor suspected to be metastatic breast carcinoma. An orbital biopsy was performed with significant hemorrhage encountered requiring extensive cautery. There was apparent clinical regression of the tumor with no signs of proptosis or eye movement restriction two years after this patient's biopsy. Histology was consistent with paraganglioma (glomus tumor).
CONCLUSION: Although we cannot rule out spontaneous regression of this unique tumor, we postulate that tissue necrosis caused by the use of cautery induced regression. Unless encapsulated and easily accessible, we suggest that the best management of this rare tumor is that of observation after being found negative for malignancy by biopsy given their propensity for slow progression and in rare cases, regression.

Entities:  

Keywords:  Glomus tumor; orbit; paraganglioma

Mesh:

Substances:

Year:  2014        PMID: 25216041     DOI: 10.3109/01676830.2014.950290

Source DB:  PubMed          Journal:  Orbit        ISSN: 0167-6830


  2 in total

1.  Orbital Paraganglioma and Succinate Dehydrogenase Staining for Genetic Testing Triage and Prognosis.

Authors:  Cesar M Salinas-La Rosa
Journal:  Ocul Oncol Pathol       Date:  2015-07-15

2.  Orbital Paraganglioma: A Systematic Review.

Authors:  Natalie Huang; Hani M Rayess; Peter F Svider; Nadim M Rayess; Adam Folbe; Paul D Langer; Jean-Anderson Eloy; Michael Carron
Journal:  J Neurol Surg B Skull Base       Date:  2017-12-27
  2 in total

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