| Literature DB >> 27162785 |
Yunyi Xin1, Chengjian Yang1, Zhijun Han1.
Abstract
Acute myocardial infarction (AMI), a common heart disease that may lead to chronic heart failure, is the leading cause of morbidity and mortality worldwide. MicroRNAs (miRNAs) are small non-coding RNAs that mediate the expression of target genes. Recently, a number of miRNAs are emerging as potential biomarkers of AMI. MiRNA-499 is a newly discovered member of miRNAs, and is mainly expressed in myocardium, the circulating levels of miRNA-499 was increased in AMI patients. This review summarizes the latest advances in the miRNA-499 study and discusses the potential of miRNA-499 to be a biomarker of AMI.Entities:
Keywords: Acute myocardial infarction (AMI); biomarker; miRNA-499
Year: 2016 PMID: 27162785 PMCID: PMC4842393 DOI: 10.21037/atm.2016.03.40
Source DB: PubMed Journal: Ann Transl Med ISSN: 2305-5839