| Literature DB >> 27160868 |
X Lin1, Q Hu1, R Zhang2, Y Hu2, X Xu3, H Lv4.
Abstract
Eighty-three carbapenem-resistant Serratia marcescens isolates were recovered from Zhejiang Provincial People's Hospital, China. The minimum inhibitory concentrations of imipenem, meropenem, and ertapenem for all isolates were 2 to >128 μg/mL. Polymerase chain reaction indicated that 63 S. marcescens isolates produced Klebsiella pneumoniae carbapenemase (KPC)-2. Clone A (15 isolates) and clone B (41 isolates) were the two dominant clones and clone A strains were gradually replaced by clone B strains between 2011 and 2014. The results indicate that blaKPC-2-positive S. marcescens emerged in our hospital as the major mechanism of carbapenem resistance.Entities:
Keywords: Carbapenem; Carbapenemase; ERIC–PCR; KPC-2; Resistance; Serratia marcescens
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Year: 2016 PMID： 27160868 DOI： 10.1016/j.jhin.2016.04.006
Source DB: PubMed Journal: J Hosp Infect ISSN： 0195-6701 Impact factor: 3.926