Literature DB >> 27158416

Promising tumor inhibiting potentials of Fisetin through PI3K/AKT/mTOR pathway.

Vazhappilly Cijo George1.   

Abstract

Entities:  

Year:  2016        PMID： 27158416      PMCID： PMC4846973     

Source DB:  PubMed          Journal:  Am J Transl Res            Impact factor:   4.060


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  9 in total

1.  Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter.

Authors:  Joo Ae Kim; Somyoung Lee; Da-Eun Kim; Moonil Kim; Byoung-Mog Kwon; Dong Cho Han
Journal:  Carcinogenesis       Date:  2015-04-03       Impact factor: 4.944

2.  Activation of reactive oxygen species/AMP activated protein kinase signaling mediates fisetin-induced apoptosis in multiple myeloma U266 cells.

Authors:  Ki Young Jang; Soo-Jin Jeong; Sun-Hee Kim; Ji Hoon Jung; Ji-Hyun Kim; Wonil Koh; Chang-Yan Chen; Sung-Hoon Kim
Journal:  Cancer Lett       Date:  2012-01-17       Impact factor: 8.679

3.  Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin.

Authors:  Naghma Khan; Farrukh Afaq; Fatima H Khusro; Vaqar Mustafa Adhami; Yewseok Suh; Hasan Mukhtar
Journal:  Int J Cancer       Date:  2011-08-26       Impact factor: 7.396

4.  Inhibition of human melanoma cell growth by the dietary flavonoid fisetin is associated with disruption of Wnt/β-catenin signaling and decreased Mitf levels.

Authors:  Deeba N Syed; Farrukh Afaq; Nityanand Maddodi; Jeremy J Johnson; Sami Sarfaraz; Adeel Ahmad; Vijayasaradhi Setaluri; Hasan Mukhtar
Journal:  J Invest Dermatol       Date:  2011-02-24       Impact factor: 8.551

Review 5.  Inhibition of Akt/mTOR signaling by the dietary flavonoid fisetin.

Authors:  Deeba N Syed; Vaqar M Adhami; Mohammad Imran Khan; Hasan Mukhtar
Journal:  Anticancer Agents Med Chem       Date:  2013-09       Impact factor: 2.505

6.  Fisetin, a dietary bioflavonoid, reverses acquired Cisplatin-resistance of lung adenocarcinoma cells through MAPK/Survivin/Caspase pathway.

Authors:  Wenlei Zhuo; Liang Zhang; Yi Zhu; Bo Zhu; Zhengtang Chen
Journal:  Am J Transl Res       Date:  2015-10-15       Impact factor: 4.060

7.  Fisetin, a novel flavonol attenuates benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice.

Authors:  Nagaiya Ravichandran; Gopalakrishnan Suresh; Balasubramanian Ramesh; Ganesan Vijaiyan Siva
Journal:  Food Chem Toxicol       Date:  2011-02-17       Impact factor: 6.023

8.  Fisetin suppresses ADAM9 expression and inhibits invasion of glioma cancer cells through increased phosphorylation of ERK1/2.

Authors:  Chien-Min Chen; Yi-Hsien Hsieh; Jin-Ming Hwang; Hsun-Jin Jan; Shu-Ching Hsieh; Shin-Huey Lin; Chung-Yu Lai
Journal:  Tumour Biol       Date:  2014-12-20

9.  Fisetin inhibits UVB-induced cutaneous inflammation and activation of PI3K/AKT/NFκB signaling pathways in SKH-1 hairless mice.

Authors:  Harish Chandra Pal; Mohammad Athar; Craig A Elmets; Farrukh Afaq
Journal:  Photochem Photobiol       Date:  2014-10-07       Impact factor: 3.421
  9 in total
  4 in total

1.  Fisetin suppresses malignant proliferation in human oral squamous cell carcinoma through inhibition of Met/Src signaling pathways.

Authors:  Yan-Shu Li; Xing-Jun Qin; Wei Dai
Journal:  Am J Transl Res       Date:  2017-12-15       Impact factor: 4.060

2.  Follicle inhibition at the primordial stage without increasing apoptosis, with a combination of everolimus, verapamil.

Authors:  Michail Pargianas; Ioannis Kosmas; Kyriaki Papageorgiou; Chrysoula Kitsou; Alexandra Papoudou-Bai; Anna Batistatou; Sofia Markoula; Styliani Salta; Alexandros Dalkalitsis; Stratis Kolibianakis; Basil C Tarlatzis; Ioannis Georgiou; Theologos M Michaelidis
Journal:  Mol Biol Rep       Date:  2020-10-20       Impact factor: 2.316

3.  MicroRNA-100 suppresses human osteosarcoma cell proliferation and chemo-resistance via ZNRF2.

Authors:  Qiang Xiao; Yu Yang; Qing An; Yong Qi
Journal:  Oncotarget       Date:  2017-05-23

Review 4.  Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential.

Authors:  Dharambir Kashyap; Vivek Kumar Garg; Hardeep Singh Tuli; Mukerrem Betul Yerer; Katrin Sak; Anil Kumar Sharma; Manoj Kumar; Vaishali Aggarwal; Sardul Singh Sandhu
Journal:  Biomolecules       Date:  2019-05-06
  4 in total

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