Literature DB >> 27153735

Influence of Previous Comorbidities and Common Complications on Motor Function after Early Surgical Treatment of Patients with Traumatic Spinal Cord Injury.

Michael Kreinest1, Lisa Ludes1, Bahram Biglari2, Maike Küffer3, Ansgar Türk2, Paul A Grützner1, Stefan Matschke1.   

Abstract

The influence of complications and comorbidities on the outcome of patients with traumatic spinal cord injury after early surgery is unclear. The aim of the current study was to analyze the influence of previous comorbidities and common complications on motor function outcome of patients with traumatic spinal cord injury if early surgery was performed. All patients with a traumatic spinal cord injury who were initially surgically treated in our hospital in the period from January 2008 to December 2013 were included in this study. Epidemiological data and previous comorbidities (cardiovascular, pulmonary, metabolic, spinal) were documented. A neurological assessment was performed using the American Spinal Injury Association (ASIA) score. Retrospectively, patients' personal data (age, gender, comorbidities) and clinical data (complications, ASIA score, motor function) were analyzed statistically. A total of 133 patients met the inclusion criteria. The level of spinal cord injury ranged from C3 to L4. Motor function was improved from 51.5 ± 24.8 to 60.1 ± 25.0 (improvement: 25.7%). The most common complications were urinary tract infection and pneumonia. There is a significant relationship between a lack of previous spinal comorbidities and a better outcome in terms of motor function. No other comorbidities or complications showed any effect on motor function outcome. The current study shows that motor function was able to be improved in patients who were given early surgery after a traumatic spinal cord injury. Common complications as well as previous cardiovascular, pulmonary, and metabolic comorbidities do not impair motor function outcome. The final motor function score is reduced if patients have previous spinal comorbidities.

Entities:  

Keywords:  comorbidity; complication; hospital stay; outcome; spinal cord injury

Mesh:

Year:  2016        PMID: 27153735     DOI: 10.1089/neu.2016.4416

Source DB:  PubMed          Journal:  J Neurotrauma        ISSN: 0897-7151            Impact factor:   5.269


  5 in total

1.  Association of Pneumonia, Wound Infection, and Sepsis with Clinical Outcomes after Acute Traumatic Spinal Cord Injury.

Authors:  Blessing N R Jaja; Fan Jiang; Jetan H Badhiwala; Ralph Schär; Shekar Kurpad; Robert G Grossman; James S Harrop; Jim D Guest; Elizabeth G Toups; Chris I Shaffrey; Bizhan Aarabi; Max Boakye; Michael G Fehlings; Jefferson R Wilson
Journal:  J Neurotrauma       Date:  2019-06-17       Impact factor: 5.269

2.  Impact of complications at admission to rehabilitation on the functional status of patients with spinal cord lesion.

Authors:  Giorgio Scivoletto; Masciullo Marcella; Pichiorri Floriana; Tamburella Federica; Molinari Marco
Journal:  Spinal Cord       Date:  2020-06-12       Impact factor: 2.772

3.  Bioinformatic Analysis of the Proteome in Exosomes Derived From Plasma: Exosomes Involved in Cholesterol Metabolism Process of Patients With Spinal Cord Injury in the Acute Phase.

Authors:  Chunshuai Wu; Jinjuan Yu; Guanhua Xu; Hong Gao; Yue Sun; Jiayi Huang; Li Sun; Xu Zhang; Zhiming Cui
Journal:  Front Neuroinform       Date:  2021-07-09       Impact factor: 4.081

4.  Influence of early extensive posterior decompression on hyponatremia and cardiopulmonary dysfunction after severe traumatic cervical spinal cord injury: A clinical observational study.

Authors:  Chaohua Yang; Gaoju Wang; Shuang Xu; Guangzhou Li; Qing Wang
Journal:  Medicine (Baltimore)       Date:  2020-07-17       Impact factor: 1.817

5.  Dynamic changes in intramedullary pressure 72 hours after spinal cord injury.

Authors:  Xin Zhang; Chang-Bin Liu; De-Gang Yang; Chuan Qin; Xue-Chao Dong; Da-Peng Li; Chao Zhang; Yun Guo; Liang-Jie Du; Feng Gao; Ming-Liang Yang; Jian-Jun Li
Journal:  Neural Regen Res       Date:  2019-05       Impact factor: 5.135

  5 in total

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