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Literature DB >> 2715327

Synthesis and secretion of phospholipase C by oral spirochetes.

R Siboo¹, W al-Joburi, M Gornitsky, E C Chan.

Abstract

Four strains of oral treponemes and Treponema phagedenis Reiter synthesize and secrete phospholipase C (PLC), which was detected by the hydrolysis of p-nitrophenylphosphorylcholine. PLC was detected in gingival crevicular fluid from diseased but not from healthy sulci. The initiation and progression of periodontal lesions may begin with the hydrolysis of membrane phospholipids by PLC.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1989 PMID： 2715327 PMCID： PMC267363 DOI： 10.1128/jcm.27.3.568-570.1989

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

19 in total

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Journal: Anal Biochem Date: 1976-05-07 Impact factor: 3.365

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Authors: M A Listgarten; S Levin
Journal: J Clin Periodontol Date: 1981-04 Impact factor: 8.728

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Authors: D Grenier; B C McBride
Journal: Infect Immun Date: 1987-12 Impact factor: 3.441

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Authors: W B Baine
Journal: J Gen Microbiol Date: 1985-06

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Journal: Infect Immun Date: 1983-11 Impact factor: 3.441

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Authors: B J Shenker; M A Listgarten; N S Taichman
Journal: J Immunol Date: 1984-04 Impact factor: 5.422

10. Flurbiprofen: a potent inhibitor of alveolar bone resorption in beagles.

Authors: R C Williams; M K Jeffcoat; M L Kaplan; P Goldhaber; H G Johnson; W J Wechter
Journal: Science Date: 1985-02-08 Impact factor: 47.728

7 in total

1. Binding properties and adhesion-mediating regions of the major sheath protein of Treponema denticola ATCC 35405.

Authors: Andrew M Edwards; Howard F Jenkinson; Martin J Woodward; David Dymock
Journal: Infect Immun Date: 2005-05 Impact factor: 3.441

2. Filamentous actin disruption and diminished inositol phosphate response in gingival fibroblasts caused by Treponema denticola.

Authors: P F Yang; M Song; D A Grove; R P Ellen
Journal: Infect Immun Date: 1998-02 Impact factor: 3.441