Valentina Forni Ogna1, Adam Ogna2, Belen Ponte3, Luca Gabutti2, Isabelle Binet4, David Conen5, Paul Erne6, Augusto Gallino7, Idris Guessous8, Daniel Hayoz9, Franco Muggli10, Fred Paccaud11, Antoinette Péchère-Bertschi12, Paolo M Suter13, Murielle Bochud11, Michel Burnier1. 1. Service of Nephrology and Hypertension, Department of Medicine, Lausanne University Hospital, Switzerland. 2. Department of Internal Medicine and Nephrology, Ospedale La Carità, Locarno, Switzerland. 3. Division of Chronic Disease, Institute of Social and Preventive Medicine, Lausanne University Hospital, Switzerland; Service of Nephrology, Geneva University Hospitals, Switzerland. 4. Service of Nephrology/Transplantation Medicine, Kantonsspital, St. Gallen, Switzerland. 5. Department of Medicine, University Hospital Basel, Switzerland. 6. Hypertension Centre, Luzern, Switzerland. 7. Cardiology Department, Ospedale San Giovanni, Bellinzona, Switzerland. 8. Division of Chronic Disease, Institute of Social and Preventive Medicine, Lausanne University Hospital, Switzerland; Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine. 9. Department of Internal Medicine and Angiology, Hôpital Cantonal, Fribourg, Switzerland. 10. Internal Medicine Praxis, Vezia, Switzerland. 11. Division of Chronic Disease, Institute of Social and Preventive Medicine, Lausanne University Hospital, Switzerland. 12. Unit of Hypertension, Departments of Specialties of Medicine and Community Medicine and Primary Care and Emergency Medicine, Geneva University Hospitals, Switzerland. 13. Clinic and Policlinic of Internal Medicine, University Hospital of Zurich, Switzerland.
Abstract
QUESTIONS UNDER STUDY: The prevalence of chronic kidney disease (CKD) is increasing worldwide, corresponding to an increased risk of cardiovascular disease. The latest study on prevalence of CKD involving the three linguistic regions of Switzerland dates back to 2002-2003 and definitions have changed since then. We aimed to assess the current prevalence and determinants of CKD in the Swiss general population. METHODS: We analysed the data of 1353 participants from a cross-sectional population-based survey performed in 2010-2012 in the three linguistic regions of Switzerland. The prevalence of CKD and the derived cardiovascular risk categories were assessed according to the Kidney Disease - Improving Global Outcomes (KDIGO) 2012 classification, using estimated glomerular filtration rate (GFR; CKD-Epidemiological Collaboration equation) and albuminuria level. Multivariate logistic regression was used to analyse factors associated with CKD. RESULTS: We included 660 men and 693 women, equally distributed in four age categories (15-29, 30-44, 45-59 and over 60 years). The overall prevalence of CKD was 10.4%. The prevalence in the low, moderate, high and very high risk KDIGO categories were 89.6%, 8.4%, 1.6% and 0.5%, respectively. The prevalence of CKD was similar in all linguistic regions. In multivariate analysis, female gender, older age, diabetes and uric acid were independently associated with CKD in persons ≥45 y. In younger participants, diabetes and lower educational level were associated with CKD. CONCLUSIONS: In the general Swiss population, CKD affects one in ten adults. Subjects older than 60 years, as well as patients with diabetes and hypertension, show a high prevalence of CKD. Systematic screening may be recommended in this population.
QUESTIONS UNDER STUDY: The prevalence of chronic kidney disease (CKD) is increasing worldwide, corresponding to an increased risk of cardiovascular disease. The latest study on prevalence of CKD involving the three linguistic regions of Switzerland dates back to 2002-2003 and definitions have changed since then. We aimed to assess the current prevalence and determinants of CKD in the Swiss general population. METHODS: We analysed the data of 1353 participants from a cross-sectional population-based survey performed in 2010-2012 in the three linguistic regions of Switzerland. The prevalence of CKD and the derived cardiovascular risk categories were assessed according to the Kidney Disease - Improving Global Outcomes (KDIGO) 2012 classification, using estimated glomerular filtration rate (GFR; CKD-Epidemiological Collaboration equation) and albuminuria level. Multivariate logistic regression was used to analyse factors associated with CKD. RESULTS: We included 660 men and 693 women, equally distributed in four age categories (15-29, 30-44, 45-59 and over 60 years). The overall prevalence of CKD was 10.4%. The prevalence in the low, moderate, high and very high risk KDIGO categories were 89.6%, 8.4%, 1.6% and 0.5%, respectively. The prevalence of CKD was similar in all linguistic regions. In multivariate analysis, female gender, older age, diabetes and uric acid were independently associated with CKD in persons ≥45 y. In younger participants, diabetes and lower educational level were associated with CKD. CONCLUSIONS: In the general Swiss population, CKD affects one in ten adults. Subjects older than 60 years, as well as patients with diabetes and hypertension, show a high prevalence of CKD. Systematic screening may be recommended in this population.
Authors: Emmanuel I Agaba; Maxwell O Akanbi; Patricia A Agaba; Amaka N Ocheke; Zumnan M Gimba; Steve Daniyam; Edith N Okeke Journal: Cardiovasc J Afr Date: 2017-08-15 Impact factor: 1.167
Authors: Tuyen Van Duong; Pei-Yu Wu; Evelyn Yang; Yuh-Feng Lin; Hung-Yi Chiou; Shwu-Huey Yang Journal: Int J Environ Res Public Health Date: 2019-12-13 Impact factor: 3.390