Literature DB >> 27152040

Outcome based on treatment protocol in patients with primary canine immune-mediated thrombocytopenia: 46 cases (2000-2013).

Margaret Ann Scuderi1, Elizabeth Snead1, Susan Mehain1, Cheryl Waldner1, Tasha Epp1.   

Abstract

This study investigated the relationship between treatment protocol, survival to discharge, and relapse in 46 dogs diagnosed with primary immune-mediated thrombocytopenia (ITP) at the Western College of Veterinary Medicine between 2000 and 2013. Treatment was at the discretion of the attending clinician and consisted of either a corticosteroid alone or a corticosteroid plus a secondary therapy. There was no association between survival to discharge and treatment protocol (P = 0.23). Of the surviving in-patients, 39% experienced a relapse. Our study failed to show a significant difference in survival and relapse based on treatment protocol.

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Year:  2016        PMID： 27152040      PMCID： PMC4827743     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  14 in total

1.  Therapeutic options for immune-mediated thrombocytopenia.

Authors:  Reid K Nakamura; Emily Tompkins; Domenico Bianco
Journal:  J Vet Emerg Crit Care (San Antonio)       Date:  2012-01-25

2.  Therapy of immune mediated thrombocytopenia. A retrospective study of 15 dogs.

Authors:  H E Jans; P J Armstrong; G S Price
Journal:  J Vet Intern Med       Date:  1990 Jan-Feb       Impact factor: 3.333

3.  Posttransfusion purpura in a dog with hemophilia A.

Authors:  K J Wardrop; D Lewis; S Marks; M Buss
Journal:  J Vet Intern Med       Date:  1997 Jul-Aug       Impact factor: 3.333

4.  Epidemiologic survey of thrombocytopenia in dogs: a report on 987 cases.

Authors:  Carol B. Grindem; Edward B. Breitschwerdt; Wayne T. Corbett; Heather E. Jans
Journal:  Vet Clin Pathol       Date:  1991       Impact factor: 1.180

5.  Comparison of platelet count recovery with use of vincristine and prednisone or prednisone alone for treatment for severe immune-mediated thrombocytopenia in dogs.

Authors:  Elizabeth A Rozanski; Mary Beth Callan; Dez Hughes; Nancy Sanders; Urs Giger
Journal:  J Am Vet Med Assoc       Date:  2002-02-15       Impact factor: 1.936

6.  A prospective randomized clinical trial of vincristine versus human intravenous immunoglobulin for acute adjunctive management of presumptive primary immune-mediated thrombocytopenia in dogs.

Authors:  K Balog; A A Huang; S O Sum; G E Moore; C Thompson; J C Scott-Moncrieff
Journal:  J Vet Intern Med       Date:  2013-03-25       Impact factor: 3.333

7.  Detection of antiplatelet antibody with a platelet immunofluorescence assay.

Authors:  A T Kristensen; D J Weiss; J S Klausner; J Laber; D J Christie
Journal:  J Vet Intern Med       Date:  1994 Jan-Feb       Impact factor: 3.333

8.  Canine idiopathic thrombocytopenia: clinical observations and long-term follow-up in 54 cases.

Authors:  D A Williams; L Maggio-Price
Journal:  J Am Vet Med Assoc       Date:  1984-09-15       Impact factor: 1.936

9.  Treatment of severe immune-mediated thrombocytopenia with human IV immunoglobulin in 5 dogs.

Authors:  Domenico Bianco; P Jane Armstrong; Robert J Washabau
Journal:  J Vet Intern Med       Date:  2007 Jul-Aug       Impact factor: 3.333

10.  Immune-mediated Hemolytic Anemia and Thrombocytopenia in the Dog: A retrospective study of 55 cases diagnosed from 1979 through 1983 at the Western College of Veterinary Medicine.

Authors:  M L Jackson; S A Kruth
Journal:  Can Vet J       Date:  1985-08       Impact factor: 1.008
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  4 in total

1.  Application of therapeutic plasma exchange in dogs with immune-mediated thrombocytopenia.

Authors:  Lucy Kopecny; Carrie A Palm; Sean Naylor; John Kirby; Larry D Cowgill
Journal:  J Vet Intern Med       Date:  2020-06-19       Impact factor: 3.333

Review 2.  Immunomodulatory and immunosuppressive drug protocols in the treatment of canine primary immune thrombocytopenia, a scoping review.

Authors:  Peter Spanner Kristiansen; Lise Nikolic Nielsen
Journal:  Acta Vet Scand       Date:  2021-12-27       Impact factor: 1.695

3.  Pharmacokinetics of Oral Prednisone at Various Doses in Dogs: Preliminary Findings Using a Naïve Pooled-Data Approach.

Authors:  Lionel Sebbag; Jonathan P Mochel
Journal:  Front Vet Sci       Date:  2020-10-19

4.  Lyophilized platelets versus cryopreserved platelets for management of bleeding in thrombocytopenic dogs: A multicenter randomized clinical trial.

Authors:  Robert Goggs; Benjamin M Brainard; Dana N LeVine; Janine Calabro; Karyn Harrell; Tracy Mills; Richard Stone; Benjamin Davidson; Christine Iacovetta; Lauren Harris; John Gicking; Mary Aslanian; Ashley Ziegler; Brenda Fulcher; Teresa Lightfoot; Meredith Miller; John Loftus; Rebecca Walton; April Blong; Jennifer Kishbaugh; Anne S Hale
Journal:  J Vet Intern Med       Date:  2020-10-05       Impact factor: 3.333
  4 in total

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