Abdussamet Batur1, Murat Atmaca2, Alpaslan Yavuz3, Mesut Ozgokce3, Aydın Bora3, Mehmet Deniz Bulut3, Harun Arslan3, Osman Toktas4, Muhammed Alpaslan3. 1. Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey baturabdussamet@gmail.com. 2. Department of Endocrinology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey. 3. Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey. 4. Department of General Surgery, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
Abstract
OBJECTIVES: The aim of this study was to detect the level of stiffness of parathyroid adenomas and to distinguish them from benign and malignant thyroid nodules using ultrasound elastography with acoustic radiation force impulse imaging. METHODS: Twenty-one patients with parathyroid adenomas and 71 patients with thyroid nodules were evaluated by acoustic radiation force impulse imaging in this study. Acoustic radiation force impulse elastograms were obtained after evaluation of the thyroid nodules, which were predicted to undergo fine-needle aspiration biopsy, and patients with a diagnosis of hyperparathyroidism, which was identified by sonography at the same time. RESULTS: An analysis of mean shear wave velocity (SWV) values for parathyroid adenomas and thyroid nodules showed that parathyroid adenomas had significantly higher stiffness levels compared to benign thyroid nodules (mean SWV ± SD, 3.09 ± 0.75 versus 2.20 ± 0.39 m/s; P < .001) and lower stiffness levels compared to malignant thyroid nodules (mean SWV, 3.09 ± 0.75 versus 3.59 ± 0.43 m/s; P < .001). CONCLUSIONS: Acoustic radiation force impulse imaging has high sensitivity and specificity for differentiating parathyroid adenomas from benign and malignant thyroid nodules. As an adjunctive tool, it can help distinguish parathyroid adenomas from thyroid nodules, including posteriorly located nodules.
OBJECTIVES: The aim of this study was to detect the level of stiffness of parathyroid adenomas and to distinguish them from benign and malignant thyroid nodules using ultrasound elastography with acoustic radiation force impulse imaging. METHODS: Twenty-one patients with parathyroid adenomas and 71 patients with thyroid nodules were evaluated by acoustic radiation force impulse imaging in this study. Acoustic radiation force impulse elastograms were obtained after evaluation of the thyroid nodules, which were predicted to undergo fine-needle aspiration biopsy, and patients with a diagnosis of hyperparathyroidism, which was identified by sonography at the same time. RESULTS: An analysis of mean shear wave velocity (SWV) values for parathyroid adenomas and thyroid nodules showed that parathyroid adenomas had significantly higher stiffness levels compared to benign thyroid nodules (mean SWV ± SD, 3.09 ± 0.75 versus 2.20 ± 0.39 m/s; P < .001) and lower stiffness levels compared to malignant thyroid nodules (mean SWV, 3.09 ± 0.75 versus 3.59 ± 0.43 m/s; P < .001). CONCLUSIONS: Acoustic radiation force impulse imaging has high sensitivity and specificity for differentiating parathyroid adenomas from benign and malignant thyroid nodules. As an adjunctive tool, it can help distinguish parathyroid adenomas from thyroid nodules, including posteriorly located nodules.
Authors: Laura Cotoi; Daniela Amzar; Ioan Sporea; Andreea Borlea; Dan Navolan; Flore Varcus; Dana Stoian Journal: Int J Endocrinol Date: 2020-03-17 Impact factor: 3.257
Authors: Jacek Baj; Robert Sitarz; Marek Łokaj; Alicja Forma; Marcin Czeczelewski; Amr Maani; Gabriella Garruti Journal: Molecules Date: 2020-04-09 Impact factor: 4.411