Literature DB >> 27147602

Ion channels find a pathway for therapeutic success.

Maria L Garcia1, Gregory J Kaczorowski2.   

Abstract

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Year:  2016        PMID： 27147602      PMCID： PMC4878490          DOI： 10.1073/pnas.1605669113

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  17 in total

Review 1.  HTS assays for developing the molecular pharmacology of ion channels.

Authors:  Owen B McManus
Journal:  Curr Opin Pharmacol       Date:  2014-02-18       Impact factor: 5.547

Review 2.  Contribution of Automated Technologies to Ion Channel Drug Discovery.

Authors:  Arturo Picones; Arlet Loza-Huerta; Pedro Segura-Chama; Cesar O Lara-Figueroa
Journal:  Adv Protein Chem Struct Biol       Date:  2016-03-03       Impact factor: 3.507

3.  Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels.

Authors:  Zhenwei Su; Emily C Brown; Weiwei Wang; Roderick MacKinnon
Journal:  Proc Natl Acad Sci U S A       Date:  2016-04-18       Impact factor: 11.205

4.  The inwardly rectifying potassium channel Kir1.1: development of functional assays to identify and characterize channel inhibitors.

Authors:  John P Felix; Birgit T Priest; Kelli Solly; Timothy Bailey; Richard M Brochu; Chou J Liu; Martin G Kohler; Laszlo Kiss; Magdalena Alonso-Galicia; Haifeng Tang; Alexander Pasternak; Gregory J Kaczorowski; Maria L Garcia
Journal:  Assay Drug Dev Technol       Date:  2012-08-10       Impact factor: 1.738

5.  Development of the predictor HERG fluorescence polarization assay using a membrane protein enrichment approach.

Authors:  David R Piper; Steve R Duff; Hildegard C Eliason; W Jack Frazee; Elizabeth A Frey; Maya Fuerstenau-Sharp; Christine Jachec; Bryan D Marks; Brian A Pollok; Mohammed Saleh Shekhani; David V Thompson; Pam Whitney; Kurt W Vogel; Stephen D Hess
Journal:  Assay Drug Dev Technol       Date:  2008-04       Impact factor: 1.738

6.  Miniaturization and HTS of a FRET-based membrane potential assay for K(ir) channel inhibitors.

Authors:  Kelli Solly; Jason Cassaday; John P Felix; Maria L Garcia; Marc Ferrer; Berta Strulovici; Laszlo Kiss
Journal:  Assay Drug Dev Technol       Date:  2008-04       Impact factor: 1.738

Review 7.  BK channel activators and their therapeutic perspectives.

Authors:  Bo H Bentzen; Søren-Peter Olesen; Lars C B Rønn; Morten Grunnet
Journal:  Front Physiol       Date:  2014-10-09       Impact factor: 4.566

8.  Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.

Authors:  Stephen G Brohawn; Ernest B Campbell; Roderick MacKinnon
Journal:  Nature       Date:  2014-12-04       Impact factor: 49.962

9.  A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels.

Authors:  Sviatoslav N Bagriantsev; Kean-Hooi Ang; Alejandra Gallardo-Godoy; Kimberly A Clark; Michelle R Arkin; Adam R Renslo; Daniel L Minor
Journal:  ACS Chem Biol       Date:  2013-06-17       Impact factor: 5.100

Review 10.  Novel screening techniques for ion channel targeting drugs.

Authors:  Alison Obergrussberger; Sonja Stölzle-Feix; Nadine Becker; Andrea Brüggemann; Niels Fertig; Clemens Möller
Journal:  Channels (Austin)       Date:  2015-11-10       Impact factor: 2.581
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  4 in total

1.  Targeting Viral Ion Channels: A Promising Strategy to Curb SARS-CoV-2.

Authors:  Anamika Singh; Isaiah T Arkin
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-24

2.  Conformational changes upon gating of KirBac1.1 into an open-activated state revealed by solid-state NMR and functional assays.

Authors:  Reza Amani; Collin G Borcik; Nazmul H Khan; Derek B Versteeg; Maryam Yekefallah; Hoa Q Do; Heather R Coats; Benjamin J Wylie
Journal:  Proc Natl Acad Sci U S A       Date:  2020-01-24       Impact factor: 11.205

Review 3.  Sperm ion channels and transporters in male fertility and infertility.

Authors:  Huafeng Wang; Luke L McGoldrick; Jean-Ju Chung
Journal:  Nat Rev Urol       Date:  2020-11-19       Impact factor: 14.432

4.  Drug-Targeted Genomes: Mutability of Ion Channels and GPCRs.

Authors:  Regan Raines; Ian McKnight; Hunter White; Kaitlyn Legg; Chan Lee; Wei Li; Peter H U Lee; Joon W Shim
Journal:  Biomedicines       Date:  2022-03-03
  4 in total

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