Literature DB >> 27141360

Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction.

Jessica Cedervall1, Anna Dimberg2, Anna-Karin Olsson1.   

Abstract

Neutrophil extracellular traps (NETs) are part of the innate immune defense against microbes, but their contribution to several non-infectious inflammatory conditions has recently been unraveled. We demonstrate that NETs accumulate in the peripheral circulation in tumor-bearing mice, causing systemic inflammation and vascular dysfuntion in organs not affected by tumor cells.

Entities:  

Keywords:  Cancer; NETs; inflammation; neutrophil extracellular traps; systemic; vascular function

Year:  2015        PMID： 27141360      PMCID： PMC4839319          DOI： 10.1080/2162402X.2015.1098803

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

1.  Neutrophil extracellular traps kill bacteria.

Authors:  Volker Brinkmann; Ulrike Reichard; Christian Goosmann; Beatrix Fauler; Yvonne Uhlemann; David S Weiss; Yvette Weinrauch; Arturo Zychlinsky
Journal:  Science       Date:  2004-03-05       Impact factor: 47.728

2.  Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus.

Authors:  Eneida Villanueva; Srilakshmi Yalavarthi; Celine C Berthier; Jeffrey B Hodgin; Ritika Khandpur; Andrew M Lin; Cory J Rubin; Wenpu Zhao; Stephen H Olsen; Matthew Klinker; David Shealy; Michael F Denny; Joel Plumas; Laurence Chaperot; Matthias Kretzler; Allen T Bruce; Mariana J Kaplan
Journal:  J Immunol       Date:  2011-05-25       Impact factor: 5.422

3.  PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock.

Authors:  Kimberly Martinod; Tobias A Fuchs; Naamah L Zitomersky; Siu Ling Wong; Melanie Demers; Maureen Gallant; Yanming Wang; Denisa D Wagner
Journal:  Blood       Date:  2015-01-26       Impact factor: 22.113

4.  Diabetes primes neutrophils to undergo NETosis, which impairs wound healing.

Authors:  Siu Ling Wong; Melanie Demers; Kimberly Martinod; Maureen Gallant; Yanming Wang; Allison B Goldfine; C Ronald Kahn; Denisa D Wagner
Journal:  Nat Med       Date:  2015-06-15       Impact factor: 53.440

5.  Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.

Authors:  Jessica Cedervall; Yanyu Zhang; Hua Huang; Lei Zhang; Julia Femel; Anna Dimberg; Anna-Karin Olsson
Journal:  Cancer Res       Date:  2015-06-12       Impact factor: 12.701

Review 6.  The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis.

Authors:  Sandra S McAllister; Robert A Weinberg
Journal:  Nat Cell Biol       Date:  2014-08       Impact factor: 28.824

Review 7.  NETosis: a new factor in tumor progression and cancer-associated thrombosis.

Authors:  Melanie Demers; Denisa D Wagner
Journal:  Semin Thromb Hemost       Date:  2014-03-03       Impact factor: 4.180

8.  PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.

Authors:  Pingxin Li; Ming Li; Michael R Lindberg; Mary J Kennett; Na Xiong; Yanming Wang
Journal:  J Exp Med       Date:  2010-08-23       Impact factor: 14.307

9.  Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Authors:  Huw D Lewis; John Liddle; Jim E Coote; Stephen J Atkinson; Michael D Barker; Benjamin D Bax; Kevin L Bicker; Ryan P Bingham; Matthew Campbell; Yu Hua Chen; Chun-Wa Chung; Peter D Craggs; Rob P Davis; Dirk Eberhard; Gerard Joberty; Kenneth E Lind; Kelly Locke; Claire Maller; Kimberly Martinod; Chris Patten; Oxana Polyakova; Cecil E Rise; Martin Rüdiger; Robert J Sheppard; Daniel J Slade; Pamela Thomas; Jim Thorpe; Gang Yao; Gerard Drewes; Denisa D Wagner; Paul R Thompson; Rab K Prinjha; David M Wilson
Journal:  Nat Chem Biol       Date:  2015-01-26       Impact factor: 15.040

10.  Extracellular histones are major mediators of death in sepsis.

Authors:  Jun Xu; Xiaomei Zhang; Rosana Pelayo; Marc Monestier; Concetta T Ammollo; Fabrizio Semeraro; Fletcher B Taylor; Naomi L Esmon; Florea Lupu; Charles T Esmon
Journal:  Nat Med       Date:  2009-10-25       Impact factor: 53.440
  10 in total
  2 in total

1.  Increased Risk of Cardiovascular Death in Breast Cancer Patients Without Chemotherapy or (and) Radiotherapy: A Large Population-Based Study.

Authors:  Tianwang Guan; Hanbin Zhang; Jinming Yang; Wenrui Lin; Kenie Wang; Miao Su; Weien Peng; Yemin Li; Yanxian Lai; Cheng Liu
Journal:  Front Oncol       Date:  2021-01-28       Impact factor: 6.244

2.  Neutrophil extracellular traps in patients with liver cirrhosis and hepatocellular carcinoma.

Authors:  Robin Zenlander; Sebastian Havervall; Maria Magnusson; Jennie Engstrand; Anna Ågren; Charlotte Thålin; Per Stål
Journal:  Sci Rep       Date:  2021-09-09       Impact factor: 4.379
  2 in total

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