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Literature DB >> 27135210

Breaking BRAF(V600E)-drug resistance by stressing mitochondria.

Chi Luo, Pere Puigserver, Hans R Widlund¹.
1. hwidlund@bwh.harvard.edu.

Abstract

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2016 PMID： 27135210 PMCID： PMC5505625 DOI： 10.1111/pcmr.12486

Source DB: PubMed Journal: Pigment Cell Melanoma Res ISSN： 1755-1471 Impact factor: 4.693

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7 in total

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Authors: Paul B Chapman; Axel Hauschild; Caroline Robert; John B Haanen; Paolo Ascierto; James Larkin; Reinhard Dummer; Claus Garbe; Alessandro Testori; Michele Maio; David Hogg; Paul Lorigan; Celeste Lebbe; Thomas Jouary; Dirk Schadendorf; Antoni Ribas; Steven J O'Day; Jeffrey A Sosman; John M Kirkwood; Alexander M M Eggermont; Brigitte Dreno; Keith Nolop; Jiang Li; Betty Nelson; Jeannie Hou; Richard J Lee; Keith T Flaherty; Grant A McArthur
Journal: N Engl J Med Date: 2011-06-05 Impact factor: 91.245

2. Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma.

Authors: Georgina V Long; Daniil Stroyakovskiy; Helen Gogas; Evgeny Levchenko; Filippo de Braud; James Larkin; Claus Garbe; Thomas Jouary; Axel Hauschild; Jean Jacques Grob; Vanna Chiarion Sileni; Celeste Lebbe; Mario Mandalà; Michael Millward; Ana Arance; Igor Bondarenko; John B A G Haanen; Johan Hansson; Jochen Utikal; Virginia Ferraresi; Nadezhda Kovalenko; Peter Mohr; Volodymyr Probachai; Dirk Schadendorf; Paul Nathan; Caroline Robert; Antoni Ribas; Douglas J DeMarini; Jhangir G Irani; Michelle Casey; Daniele Ouellet; Anne-Marie Martin; Ngocdiep Le; Kiran Patel; Keith Flaherty
Journal: N Engl J Med Date: 2014-09-29 Impact factor: 91.245

3. PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.

Authors: Francisca Vazquez; Ji-Hong Lim; Helen Chim; Kavita Bhalla; Geoff Girnun; Kerry Pierce; Clary B Clish; Scott R Granter; Hans R Widlund; Bruce M Spiegelman; Pere Puigserver
Journal: Cancer Cell Date: 2013-02-14 Impact factor: 31.743

4. Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors.

Authors: Gao Zhang; Dennie T Frederick; Lawrence Wu; Zhi Wei; Clemens Krepler; Satish Srinivasan; Young Chan Chae; Xiaowei Xu; Harry Choi; Elaida Dimwamwa; Omotayo Ope; Batool Shannan; Devraj Basu; Dongmei Zhang; Manti Guha; Min Xiao; Sergio Randell; Katrin Sproesser; Wei Xu; Jephrey Liu; Giorgos C Karakousis; Lynn M Schuchter; Tara C Gangadhar; Ravi K Amaravadi; Mengnan Gu; Caiyue Xu; Abheek Ghosh; Weiting Xu; Tian Tian; Jie Zhang; Shijie Zha; Qin Liu; Patricia Brafford; Ashani Weeraratna; Michael A Davies; Jennifer A Wargo; Narayan G Avadhani; Yiling Lu; Gordon B Mills; Dario C Altieri; Keith T Flaherty; Meenhard Herlyn
Journal: J Clin Invest Date: 2016-04-04 Impact factor: 14.808

5. Improvement of the model systems.

Authors: H E Skipper
Journal: Cancer Res Date: 1969-12 Impact factor: 12.701

6. Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

Authors: Rizwan Haq; Jonathan Shoag; Pedro Andreu-Perez; Satoru Yokoyama; Hannah Edelman; Glenn C Rowe; Dennie T Frederick; Aeron D Hurley; Abhinav Nellore; Andrew L Kung; Jennifer A Wargo; Jun S Song; David E Fisher; Zolt Arany; Hans R Widlund
Journal: Cancer Cell Date: 2013-03-07 Impact factor: 31.743

7. Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells.

Authors: Alexander Roesch; Adina Vultur; Ivan Bogeski; Huan Wang; Katharina M Zimmermann; David Speicher; Christina Körbel; Matthias W Laschke; Phyllis A Gimotty; Stephan E Philipp; Elmar Krause; Sylvie Pätzold; Jessie Villanueva; Clemens Krepler; Mizuho Fukunaga-Kalabis; Markus Hoth; Boris C Bastian; Thomas Vogt; Meenhard Herlyn
Journal: Cancer Cell Date: 2013-06-10 Impact factor: 31.743

7 in total

3 in total