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Literature DB >> 27134640

Using the Power of Organic Synthesis for Engineering the Interactions of Nanoparticles with Biological Systems.

Tsukasa Mizuhara¹, Daniel F Moyano¹, Vincent M Rotello¹.

Abstract

The surface properties of nanoparticles (NPs) dictate their interaction with the outside world. The use of precisely designed molecular ligands to control NP surface properties provides an important toolkit for modulating their interaction with biological systems, facilitating their use in biomedicine. In this review we will discuss the application of the atom-by-atom control provided by organic synthesis to the generation of engineered nanoparticles, with emphasis on how the functionalization of NPs with these "small" organic molecules (Mw < 1,000) can be used to engineer NPs for a wide range of applications.

Entities: CellLine Chemical Disease Gene Species

Year: 2016 PMID： 27134640 PMCID： PMC4847953 DOI： 10.1016/j.nantod.2015.11.002

Source DB: PubMed Journal: Nano Today ISSN： 1748-0132 Impact factor: 20.722

69 in total

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Journal: J Med Chem Date: 2011-02-03 Impact factor: 7.446

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Journal: Nat Nanotechnol Date: 2013-01-20 Impact factor: 39.213

3. Supramolecular Host-Guest Chemistry-Based Folate/Riboflavin Functionalization and Cancer Cell Labeling of Nanoparticles.

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Journal: ACS Omega Date: 2017-12-14

Review 4. Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design.

Authors: Rui Huang; David C Luther; Xianzhi Zhang; Aarohi Gupta; Samantha A Tufts; Vincent M Rotello
Journal: Nanomaterials (Basel) Date: 2021-04-13 Impact factor: 5.076

4 in total