Literature DB >> 27134632

Conservative surgery for the treatment of osteonecrosis of the femoral head: current options.

Elena Gasbarra1, Fabio Luigi Perrone2, Jacopo Baldi2, Vincenzo Bilotta2, Antimo Moretti3, Umbertto Tarantino1.   

Abstract

The prevention of femoral head collapse and the maintenance of hip function would represent a substantial achievement in the treatment of osteonecrosis of the femoral head; however it is difficult to identify appropriate treatment protocols to manage patients with pre-collapse avascular necrosis in order to obtain a successful outcome in joint preserving procedures. Conservative treatments, including pharmacological management and biophysical modalities, are not supported by any evidence and require further investigation. The appropriate therapeutic approach has not been identified. The choice of surgical procedures is based on patient clinical conditions and anatomopathological features; preservation of the femoral head by core decompression may be attempted in younger patients without head collapse. Biological factors, such as bone morphogenetic proteins and bone marrow stem cells, would improve the outcome of core decompression. Another surgical procedure proposed for the treatment of avascular necrosis consists of large vascularized cortical bone grafts, but its use is not yet common due to surgical technical issues. Use of other surgical technique, such as osteotomies, is controversial, since arthroplasty is considered as the first option in case of severe femoral head collapse without previous intervention.

Entities:  

Keywords:  bone transplantation; femur head necrosis; orthopedic procedures; osteonecrosis

Year:  2016        PMID: 27134632      PMCID: PMC4832404          DOI: 10.11138/ccmbm/2015.12.3s.043

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN: 1724-8914


  81 in total

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Authors:  M A Jacobs; D S Hungerford; K A Krackow
Journal:  J Bone Joint Surg Br       Date:  1989-03

2.  Free vascularized fibula grafting for the treatment of osteonecrosis of the femoral head.

Authors:  D G Sotereanos; A Y Plakseychuk; H E Rubash
Journal:  Clin Orthop Relat Res       Date:  1997-11       Impact factor: 4.176

3.  Results of multiple drilling compared with those of conventional methods of core decompression.

Authors:  Won Seok Song; Jeong Joon Yoo; Young-Min Kim; Hee Joong Kim
Journal:  Clin Orthop Relat Res       Date:  2007-01       Impact factor: 4.176

4.  Multiple drilling compared with standard core decompression for avascular necrosis of the femoral head in sickle cell disease patients.

Authors:  Abdullah Al Omran
Journal:  Arch Orthop Trauma Surg       Date:  2013-03-15       Impact factor: 3.067

5.  Nonvascularized bone grafting defers joint arthroplasty in hip osteonecrosis.

Authors:  Thorsten M Seyler; David R Marker; Slif D Ulrich; Tobias Fatscher; Michael A Mont
Journal:  Clin Orthop Relat Res       Date:  2008-05       Impact factor: 4.176

Review 6.  Core decompression versus nonoperative management for osteonecrosis of the hip.

Authors:  M A Mont; J J Carbone; A C Fairbank
Journal:  Clin Orthop Relat Res       Date:  1996-03       Impact factor: 4.176

7.  Long term followup of thorough debridement and cancellous bone grafting of the femoral head for avascular necrosis.

Authors:  M P Rosenwasser; J P Garino; H A Kiernan; C B Michelsen
Journal:  Clin Orthop Relat Res       Date:  1994-09       Impact factor: 4.176

Review 8.  Stem cell- and growth factor-based regenerative therapies for avascular necrosis of the femoral head.

Authors:  Lars Rackwitz; Lars Eden; Stephan Reppenhagen; Johannes C Reichert; Franz Jakob; Heike Walles; Oliver Pullig; Rocky S Tuan; Maximilian Rudert; Ulrich Nöth
Journal:  Stem Cell Res Ther       Date:  2012-02-22       Impact factor: 6.832

9.  Mesenchymal stem cells.

Authors:  A I Caplan
Journal:  J Orthop Res       Date:  1991-09       Impact factor: 3.494

10.  Short term clinical outcome of a porous tantalum implant for the treatment of advanced osteonecrosis of the femoral head.

Authors:  Mélissa Nadeau; Chantal Séguin; John S Theodoropoulos; Edward J Harvey
Journal:  Mcgill J Med       Date:  2007-01
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  6 in total

Review 1.  Clinical effect of hyperbaric oxygen therapy in the treatment of femoral head necrosis : A systematic review and meta-analysis.

Authors:  Wei Li; Ziliang Ye; Wei Wang; Kun Wang; Lang Li; Dewei Zhao
Journal:  Orthopade       Date:  2017-05       Impact factor: 1.087

2.  Autologous bone marrow derived mesenchymal stem cell therapy for osteonecrosis of femoral head: A systematic overview of overlapping meta-analyses.

Authors:  Madhan Jeyaraman; Sathish Muthu; Rashmi Jain; Manish Khanna
Journal:  J Clin Orthop Trauma       Date:  2020-11-26

Review 3.  Efficacy and safety of stem cell therapy for the early-stage osteonecrosis of femoral head: a systematic review and meta-analysis of randomized controlled trials.

Authors:  Lianghao Mao; Pan Jiang; Xuan Lei; Chenlie Ni; Yiming Zhang; Bing Zhang; Qiping Zheng; Dapeng Li
Journal:  Stem Cell Res Ther       Date:  2020-10-19       Impact factor: 6.832

Review 4.  Recent perspectives on the association between osteonecrosis and bone mineral density decline in childhood acute lymphoblastic leukemia.

Authors:  Jenneke E van Atteveld; Demi Tc de Winter; Rob Pieters; Sebastian Jcmm Neggers; Marry M van den Heuvel-Eibrink
Journal:  Fac Rev       Date:  2021-06-23

Review 5.  Osteonecrosis of the Femoral Head: Etiology, Investigations, and Management.

Authors:  Shakoor A Baig; M N Baig
Journal:  Cureus       Date:  2018-08-21

6.  Preliminary experience in the treatment of hip necrosis with BIOS screws associated with growth factors.

Authors:  Giacomo Strigini; Laura Ghidoni; Fabrizio Quattrini; Giorgio Bellina; Corrado Ciatti; Caterina Fiazza; Pietro Maniscalco
Journal:  Acta Biomed       Date:  2020-03-19
  6 in total

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