Literature DB >> 27132016

Patient Satisfaction With Collagenase.

Jack Bradley1, David Warwick2.   

Abstract

PURPOSE: To establish patient satisfaction after collagenase clostridium histolyticum (CCH) injection.
METHODS: In a cross-sectional study, 213 patients who had been treated for Dupuytren disease with CCH were reviewed between 37 and 1421 days after injection.
RESULTS: A total of 73% of the patients were very satisfied or satisfied, and 21% were dissatisfied; 75% would probably or definitely have CCH again, whereas 17% probably or definitely would not. We found that satisfaction and willingness to undergo a second treatment decreased over time and had a negative relationship with recurrence. Dissatisfaction was greater in those with a poor initial outcome but not in those with an initial complication. Of 212 patients, 78 had previously experienced surgery for Dupuytren disease of whom 71% would prefer CCH to surgery and 15% the converse. Satisfaction shows a relationship with function as measured by both QuickDASH and the Southampton Dupuytren Scoring Scheme.
CONCLUSIONS: Patient satisfaction with CCH is generally high but deteriorates over time as the disease recurs. To manage patient expectation, this issue should be made explicit to patients in the consent process. CLINICAL RELEVANCE: Overall satisfaction with CCH is high, with initial satisfaction rates especially good. Forewarning of complications and recurrence can help maintain satisfaction levels.
Copyright © 2016 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Collagenase; collagenase clostridium histolyticum; complications; patient-related outcome measures; satisfaction

Mesh:

Substances:

Year:  2016        PMID: 27132016     DOI: 10.1016/j.jhsa.2016.03.003

Source DB:  PubMed          Journal:  J Hand Surg Am        ISSN: 0363-5023            Impact factor:   2.230


  8 in total

1.  Seven-year clinical outcomes after collagenase injection in patients with Dupuytren's disease: A prospective study.

Authors:  Rocco De Vitis; Marco Passiatore; Andrea Perna; Silvia Careri; Vitale Cilli; Giuseppe Taccardo
Journal:  J Orthop       Date:  2020-03-29

2.  Treatment of Dupuytren's Contracture With Collagenase: A Systematic Review.

Authors:  Alexis B Sandler; John P Scanaliato; Thomas Dennis; Gilberto A Gonzalez Trevizo; Sorana Raiciulescu; Leon Nesti; John C Dunn
Journal:  Hand (N Y)       Date:  2021-01-21

3.  DupuytrEn Treatment EffeCtiveness Trial (DETECT): a protocol for prospective, randomised, controlled, outcome assessor-blinded, three-armed parallel 1:1:1, multicentre trial comparing the effectiveness and cost of collagenase clostridium histolyticum, percutaneous needle fasciotomy and limited fasciectomy as short-term and long-term treatment strategies in Dupuytren's contracture.

Authors:  Mikko P Räisänen; Teemu Karjalainen; Harry Göransson; Aleksi Reito; Hannu Kautiainen; Antti Malmivaara; Olli V Leppänen
Journal:  BMJ Open       Date:  2018-03-28       Impact factor: 2.692

4.  Dupuytren's disease: using needles more across the world.

Authors:  David Warwick; Paul Nm Werker; Gary Pess; Hitoshi Hirata; David J Hunter-Smith
Journal:  J Hand Surg Eur Vol       Date:  2021-09-09

5.  Collagenase Clostridium histolyticum Injection Therapy Improves Health-related Quality of Life in Patients with Dupuytren's Disease.

Authors:  Takuro Kuboi; Tsuyoshi Tajika; Fumitaka Endo; Wataru Goto; Ichiro Nakajima; Satoshi Hasegawa; Daisuke Nakajima; Takafumi Hasokawa; Hirotaka Chikuda
Journal:  Prog Rehabil Med       Date:  2021-05-26

Review 6.  Cytokine Targeted Therapy for Dupuytren's Disease.

Authors:  Latha Satish
Journal:  EBioMedicine       Date:  2018-07-18       Impact factor: 8.143

7.  Collagenase injections for Dupuytren disease: 3-year treatment outcomes and predictors of recurrence in 89 hands.

Authors:  Jesper Nordenskjöld; Anna Lauritzson; Anna Åkesson; Isam Atroshi
Journal:  Acta Orthop       Date:  2019-09-10       Impact factor: 3.717

8.  Return-to-Function Following Treatment of Dupuytren Contracture With Collagenase Clostridium Histolyticum Versus Fasciectomy.

Authors:  Victoria M Divino; Mitch DeKoven; David Hurley
Journal:  Hand (N Y)       Date:  2020-06-07
  8 in total

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