Literature DB >> 27131231

Comparing Prognostic Tools for Cancer Screening: Considerations for Clinical Practice and Performance Assessment.

Craig Evan Pollack1,2, Amanda L Blackford2, Nancy L Schoenborn1, Cynthia M Boyd1, Kimberly S Peairs1, Eva H DuGoff3.   

Abstract

OBJECTIVES: To compare the agreement and rates of cancer screening using four prognostic tools that require different types of clinical information.
DESIGN: Observational retrospective cohort study.
SETTING: 2009 and 2010 waves of the Medicare Current Beneficiary Survey. PARTICIPANTS: Adults aged 66-90 with survey and claims data (N = 9,469). MEASUREMENTS: Agreement between four indices predicting short-term (4-5 years) and long-term (9-10 years) survival; self-reported breast and prostate cancer screening.
RESULTS: Agreement between the four prognostic tools was high. Pearson correlation coefficients ranged from 0.63 to 0.90 for short-term survival and 0.68 to 0.94 for long-term survival. When defining limited short-term life expectancy as less than 25% chance of surviving 4 or 5 years, all four tools agreed in 96.4% of the sample. All four tools agreed in their placement of participants into limited or not-limited long-term life expectancy in 77.1% of participants (<25% chance of surviving 9 or 10 years). Rates of cancer screening were similarly high in individuals with limited long-term life expectancy regardless of the tool used: greater than 31% for mammographic screening in women and greater than 69% for prostate cancer screening.
CONCLUSION: There is substantial agreement among different prognostic tools for short- and long-term survival in Medicare beneficiaries. The high rates of cancer screening of individuals with limited life expectancy suggest the importance of incorporating tools into clinical decision-making.
© 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

Entities:  

Keywords:  cancer screening; life expectancy; prognosis

Mesh:

Year:  2016        PMID: 27131231      PMCID: PMC4882245          DOI: 10.1111/jgs.14089

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


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