Literature DB >> 27128785

Common Factors in Pediatric Psychiatry: A Review of Essential and Adjunctive Mechanisms of Treatment Outcome.

Alessandro S De Nadai1,2,3, Marc S Karver3, Tanya K Murphy1,2, Mark A Cavitt2,4, Jeffrey L Alvaro2,4, Michael Bengtson5, Saundra Stock2, Andrew C Rakhshani3, Eric A Storch1,2,3,4,6.   

Abstract

OBJECTIVE: The purpose of this article is to review the literature on hypothesized behavioral correlates of pharmacotherapy treatment response. A particular focus is placed on what have been referred to as "common factors" across mental health treatments, including medication adherence, therapeutic alliance, motivation for behavior change, and expectancies for positive treatment outcomes. These understudied factors may provide unique explanations for mechanisms of symptom change, patient risk as a result of protocol deviation, and attenuated treatment outcomes.
METHOD: A literature search was conducted to evaluate the relationship between treatment processes in pediatric psychiatry and medication adherence, therapeutic alliance, motivation for behavior change, and expectancies for positive treatment outcomes.
RESULTS: Substantial variability and room for improvement was identified for each common factor. Behavioral protocols have already been developed to address many aspects of common factors in pediatric psychiatric treatment, but are not yet a part of many practice parameters.
CONCLUSION: Interventions to improve common factors can be used immediately in tandem with psychopharmacological interventions to provide increased symptom relief and reduce patient risk. Furthermore, incorporating instruction in common factors interventions can positively affect training of future providers and enhance understanding of the mechanisms of effect of medications. An increased focus on common factors, with a particular emphasis on quantifying the magnitude and mechanisms of their effects on psychopharmacological interventions stand to benefit child patients, their families, treatment providers, training facilities, and pharmaceutical manufacturers.

Entities:  

Keywords:  adherence; alliance; common factors; expectancies; motivation

Mesh:

Substances:

Year:  2016        PMID: 27128785      PMCID: PMC5326981          DOI: 10.1089/cap.2015.0263

Source DB:  PubMed          Journal:  J Child Adolesc Psychopharmacol        ISSN: 1044-5463            Impact factor:   2.576


  107 in total

1.  The path to personalized medicine.

Authors:  Margaret A Hamburg; Francis S Collins
Journal:  N Engl J Med       Date:  2010-06-15       Impact factor: 91.245

Review 2.  Promoting adherence to psychotropic medication for youth-part 1.

Authors:  Teena M McGuinness; Julie Worley
Journal:  J Psychosoc Nurs Ment Health Serv       Date:  2010-09-22       Impact factor: 1.098

3.  Enhancing patient adherence: outcomes of medication alliance training on therapeutic alliance, insight, adherence, and psychopathology with mental health patients.

Authors:  Mitchell K Byrne; Frank P Deane
Journal:  Int J Ment Health Nurs       Date:  2011-02-18       Impact factor: 3.503

4.  The placebo effect revisited: lessons learned to date.

Authors:  Irving Kirsch
Journal:  Complement Ther Med       Date:  2013-01-05       Impact factor: 2.446

5.  Stages of change.

Authors:  John C Norcross; Paul M Krebs; James O Prochaska
Journal:  J Clin Psychol       Date:  2011-02

Review 6.  A literature review to identify interventions to improve the use of medicines in children.

Authors:  I Costello; I C K Wong; A J Nunn
Journal:  Child Care Health Dev       Date:  2004-11       Impact factor: 2.508

7.  Patient predictors of response to psychotherapy and pharmacotherapy: findings in the NIMH Treatment of Depression Collaborative Research Program.

Authors:  S M Sotsky; D R Glass; M T Shea; P A Pilkonis; J F Collins; I Elkin; J T Watkins; S D Imber; W R Leber; J Moyer
Journal:  Am J Psychiatry       Date:  1991-08       Impact factor: 18.112

8.  Attitudes toward attention-deficit hyperactivity disorder (ADHD) treatment: parents' and children's perspectives.

Authors:  Itai Berger; Talia Dor; Yoram Nevo; Gil Goldzweig
Journal:  J Child Neurol       Date:  2008-05-16       Impact factor: 1.987

9.  Medication use in US youth with mental disorders.

Authors:  Kathleen R Merikangas; Jian-ping He; Judith Rapoport; Benedetto Vitiello; Mark Olfson
Journal:  JAMA Pediatr       Date:  2013-02       Impact factor: 16.193

10.  Motivation to change as a predictor of treatment response in obsessive compulsive disorder.

Authors:  Anthony Pinto; Angela Marinilli Pinto; Fugen Neziroglu; Jose A Yaryura-Tobias
Journal:  Ann Clin Psychiatry       Date:  2007 Apr-Jun       Impact factor: 1.567

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  3 in total

1.  Self-Efficacy As a Target for Neuroscience Research on Moderators of Treatment Outcomes in Pediatric Anxiety.

Authors:  Krystal M Lewis; Chika Matsumoto; Elise Cardinale; Emily L Jones; Andrea L Gold; Argyris Stringaris; Ellen Leibenluft; Daniel S Pine; Melissa A Brotman
Journal:  J Child Adolesc Psychopharmacol       Date:  2020-03-11       Impact factor: 2.576

2.  Do adolescents consider mind-body skills groups an acceptable treatment for depression: results from a pilot study.

Authors:  Lindsey D Cunningham; Eduardo F Salgado; Matthew C Aalsma; Jennifer M Garabrant; Julie K Staples; James S Gordon; Michelle P Salyers
Journal:  BMC Pediatr       Date:  2021-10-27       Impact factor: 2.125

3.  Adding the missing voice: How self-report of autistic youth self-report on an executive functioning rating scale compares to parent report and that of youth with attention deficit hyperactivity disorder or neurotypical development.

Authors:  Lauren Kenworthy; Alyssa Verbalis; Julia Bascom; Sharon daVanport; John F Strang; Cara Pugliese; Andrew Freeman; Charlotte Jeppsen; Anna C Armour; Geneva Jost; Kristina Hardy; Gregory L Wallace
Journal:  Autism       Date:  2021-07-09
  3 in total

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