Literature DB >> 27123087

Diagnostic accuracy of pre-operative imaging findings in presumed clinical T1a renal cell carcinomas.

Kazufumi Nakashima1, Yasuhide Kitagawa1, Kouji Izumi1, Atsushi Mizokami1, Toshifumi Gabata2, Mikio Namiki1.   

Abstract

Despite the development of recent imaging modalities, certain pathological misdiagnoses remain for surgical specimens of presumed small renal cell carcinomas (RCCs). In the present study, a retrospective analysis of benign pathological lesions diagnosed as small RCC prior to surgery was performed. In total, the cases of 196 sporadic renal tumors that was surgically treated as clinical T1a RCCs were reviewed, and the accuracy of the pathological diagnoses was calculated. The pre-operative findings for benign pathological lesions was investigated, and the lesions were observed in 13 (6.63%) of the 196 tumors. Pre-operative computed tomography images were obtained in all cases, and magnetic resonance images were available in 10 cases. The diagnostic accuracy of imaging modalities was significantly lower in the tumors with a diameter of ≤20 mm. In all cases, the possible pathological diagnosis of RCC could not be excluded even by retrospective imaging analysis. Several benign pathological lesions were found in small renal masses presumed to be clinical T1a RCC. In conclusion, there may be limitations to the pre-operative imaging for certain types of small renal mass.

Entities:  

Keywords:  benign pathology; clinical T1a renal cell carcinoma; pre-operative imaging; small renal mass

Year:  2016        PMID: 27123087      PMCID: PMC4840990          DOI: 10.3892/ol.2016.4330

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  26 in total

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2.  Correlation between radiological and histopathological findings in patients undergoing nephrectomy for presumed renal cell carcinoma on computed tomography scan at Grey's Hospital.

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