S I Shakir1, M Pelmus2, A Florea2, J F Boileau3, M C Guiot4, S Di Maio5, T M Muanza1. 1. Department of Radiation Oncology, Jewish General Hospital, McGill University, Montreal, QC; 2. Department of Pathology, Jewish General Hospital, McGill University, Montreal, QC; 3. Department of Surgery, Jewish General Hospital, McGill University, Montreal, QC; 4. Department of Pathology, Montreal Neurological Institute, McGill University, Montreal, QC; 5. Department of Neurosurgery, Jewish General Hospital, McGill University, Montreal, QC.
Abstract
CLINICAL SCENARIO: During routine staging work-up for a left breast mass, a 68-year-old woman complained of dysphagia and dysphonia. During further investigations, a left-sided lesion at the foramen magnum was observed on brain imaging. Both lesions were biopsied and showed a classical chordoma. MANAGEMENT: The skull-base lesion and the breast lesion were surgically resected, and adjuvant radiotherapy was given. SUMMARY: Chordoma is a rare primary central nervous system tumour that seldom metastasizes. The lung is the most common site of metastasis. Synchronous breast metastasis from a skull-base chordoma is very rare, and a safe management option includes a maximum resection followed by adjuvant radiotherapy.
CLINICAL SCENARIO: During routine staging work-up for a left breast mass, a 68-year-old woman complained of dysphagia and dysphonia. During further investigations, a left-sided lesion at the foramen magnum was observed on brain imaging. Both lesions were biopsied and showed a classical chordoma. MANAGEMENT: The skull-base lesion and the breast lesion were surgically resected, and adjuvant radiotherapy was given. SUMMARY:Chordoma is a rare primary central nervous system tumour that seldom metastasizes. The lung is the most common site of metastasis. Synchronous breast metastasis from a skull-base chordoma is very rare, and a safe management option includes a maximum resection followed by adjuvant radiotherapy.
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