Literature DB >> 27120442

Intolerable secretion and diabetes in tolerant transgenic mice, revisited.

John A Todd1.   

Abstract

A new mouse model linking diabetes, insulin secretion and autoimmunity with a high-fat diet supports a shared mechanism for type 1 (T1D) and type 2 (T2D) diabetes. In this model, the protein secretion system of insulin-producing pancreatic beta cells is stressed, leading to increased beta cell apoptosis and diabetes via reduced levels of the transcription factor GLIS3, a pathogenic pathway that can be mimicked by a high-fat diet.

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Year:  2016        PMID： 27120442     DOI： 10.1038/ng.3560

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  15 in total

1.  Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion.

Authors:  Thomas Delong; Timothy A Wiles; Rocky L Baker; Brenda Bradley; Gene Barbour; Richard Reisdorph; Michael Armstrong; Roger L Powell; Nichole Reisdorph; Nitesh Kumar; Colleen M Elso; Megan DeNicola; Rita Bottino; Alvin C Powers; David M Harlan; Sally C Kent; Stuart I Mannering; Kathryn Haskins
Journal:  Science       Date:  2016-02-12       Impact factor: 47.728

2.  Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes.

Authors:  I Truyen; P De Pauw; P N Jørgensen; C Van Schravendijk; O Ubani; K Decochez; E Vandemeulebroucke; I Weets; R Mao; D G Pipeleers; F K Gorus
Journal:  Diabetologia       Date:  2005-10-07       Impact factor: 10.122

3.  Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

Authors:  Valérie Senée; Claude Chelala; Sabine Duchatelet; Daorong Feng; Hervé Blanc; Jack-Christophe Cossec; Céline Charon; Marc Nicolino; Pascal Boileau; Douglas R Cavener; Pierre Bougnères; Doris Taha; Cécile Julier
Journal:  Nat Genet       Date:  2006-05-21       Impact factor: 38.330

Review 4.  Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.

Authors:  Jinhong Sun; Jingqiu Cui; Qing He; Zheng Chen; Peter Arvan; Ming Liu
Journal:  Mol Aspects Med       Date:  2015-01-08

Review 5.  ER stress and development of type 1 diabetes.

Authors:  Feyza Engin
Journal:  J Investig Med       Date:  2016-01       Impact factor: 2.895

6.  Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.

Authors:  Elin Hall; Petr Volkov; Tasnim Dayeh; Karl Bacos; Tina Rönn; Marloes Dekker Nitert; Charlotte Ling
Journal:  BMC Med       Date:  2014-06-23       Impact factor: 8.775

7.  GLP-1 receptor agonist attenuates endoplasmic reticulum stress-mediated β-cell damage in Akita mice.

Authors:  Shunsuke Yamane; Yoshiyuki Hamamoto; Shin-Ichi Harashima; Norio Harada; Akihiro Hamasaki; Kentaro Toyoda; Kazuyo Fujita; Erina Joo; Yutaka Seino; Nobuya Inagaki
Journal:  J Diabetes Investig       Date:  2011-04-07       Impact factor: 4.232

8.  Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

Authors:  Daniel A Cunha; Laurence Ladrière; Fernanda Ortis; Mariana Igoillo-Esteve; Esteban N Gurzov; Roberto Lupi; Piero Marchetti; Décio L Eizirik; Miriam Cnop
Journal:  Diabetes       Date:  2009-08-31       Impact factor: 9.461

9.  Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.

Authors:  James Dooley; Lei Tian; Susann Schonefeldt; Viviane Delghingaro-Augusto; Josselyn E Garcia-Perez; Emanuela Pasciuto; Daniele Di Marino; Edward J Carr; Nikolay Oskolkov; Valeriya Lyssenko; Dean Franckaert; Vasiliki Lagou; Lut Overbergh; Jonathan Vandenbussche; Joke Allemeersch; Genevieve Chabot-Roy; Jane E Dahlstrom; D Ross Laybutt; Nikolai Petrovsky; Luis Socha; Kris Gevaert; Anton M Jetten; Diether Lambrechts; Michelle A Linterman; Chris C Goodnow; Christopher J Nolan; Sylvie Lesage; Susan M Schlenner; Adrian Liston
Journal:  Nat Genet       Date:  2016-03-21       Impact factor: 38.330

10.  GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim.

Authors:  Tatiane C Nogueira; Flavia M Paula; Olatz Villate; Maikel L Colli; Rodrigo F Moura; Daniel A Cunha; Lorella Marselli; Piero Marchetti; Miriam Cnop; Cécile Julier; Decio L Eizirik
Journal:  PLoS Genet       Date:  2013-05-30       Impact factor: 5.917
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  5 in total

1.  Constitutive alterations in vesicular trafficking increase the sensitivity of cells from celiac disease patients to gliadin.

Authors:  Giuliana Lania; Merlin Nanayakkara; Mariantonia Maglio; Renata Auricchio; Monia Porpora; Mariangela Conte; Maria Antonietta De Matteis; Riccardo Rizzo; Alberto Luini; Valentina Discepolo; Riccardo Troncone; Salvatore Auricchio; Maria Vittoria Barone
Journal:  Commun Biol       Date:  2019-05-20

2.  Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine.

Authors:  Miriam S Udler; Mark I McCarthy; Jose C Florez; Anubha Mahajan
Journal:  Endocr Rev       Date:  2019-12-01       Impact factor: 19.871

Review 3.  Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome-Strategies for In Vivo Administration: Part-II.

Authors:  Raquel Vieira; Selma B Souto; Elena Sánchez-López; Ana López Machado; Patricia Severino; Sajan Jose; Antonello Santini; Amelia M Silva; Ana Fortuna; Maria Luisa García; Eliana B Souto
Journal:  J Clin Med       Date:  2019-08-28       Impact factor: 4.241

Review 4.  Emerging Roles of Myeloid-Derived Suppressor Cells in Diabetes.

Authors:  Shiqi Wang; Qian Tan; Yayi Hou; Huan Dou
Journal:  Front Pharmacol       Date:  2021-12-16       Impact factor: 5.810

Review 5.  β-Cell failure in diabetes: Common susceptibility and mechanisms shared between type 1 and type 2 diabetes.

Authors:  Hiroshi Ikegami; Naru Babaya; Shinsuke Noso
Journal:  J Diabetes Investig       Date:  2021-06-16       Impact factor: 4.232
  5 in total

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