Literature DB >> 27119474

Use of complementary medicine in metastatic melanoma patients treated with ipilimumab within a clinical trial.

Jutta Huebner1, Peter Mohr2, Jan-Christoph Simon3, Michael Fluck4, Carola Berking5, Lisa Zimmer6, Carmen Loquai7.   

Abstract

BACKGROUND AND OBJECTIVES: In Germany, 40-90 % of all cancer patients use complementary and alternative medicine (CAM). So far, no data are available on the use of CAM by melanoma patients. The objective of our study was to gather data on CAM use, sources of information, and goals of patients with metastatic melanoma. PATIENTS AND METHODS: One hundred and fifty-six patients from 25 study centers participated in the DecOG-MM-PAL-Multibasket Study. These individuals were also asked to participate in a side study addressing CAM use. A standardized CAM questionnaire was distributed at defined points during the treatment.
RESULTS: Overall, 55 questionnaires from 32 (21 %) melanoma patients were received. Of those, 17 (53 %) stated an interest in CAM, and seven (22 %) actually used CAM. Family and friends were the main source of information (31 %), followed by physicians (19 %). The main reasons for using CAM were boosting the immune system (41 %) and strengthening the body (34 %). Supplements (vitamins and trace elements) were most commonly used (28 %).
CONCLUSIONS: A relatively high number of metastatic melanoma patients used CAM despite their participation in a clinical trial. Interactions may be due to biologically based CAM, especially immunomodulatory CAM strategies. In order to avoid risks, communication between physicians and patients should be improved.
© 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

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Keywords:  Complementary and alternative medicine; clinical trial; information; interactions; ipilimumab; melanoma

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Year:  2016        PMID: 27119474     DOI: 10.1111/ddg.12750

Source DB:  PubMed          Journal:  J Dtsch Dermatol Ges        ISSN: 1610-0379            Impact factor:   5.584


  1 in total

1.  Blood concentrations of vitamins B1, B6, B12, C and D and folate in palliative care patients: Results of a cross-sectional study.

Authors:  Claudia Vollbracht; Peter W Gündling; Karin Kraft; Iris Friesecke
Journal:  J Int Med Res       Date:  2019-09-23       Impact factor: 1.671

  1 in total

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