Literature DB >> 27117319

Combating radiation therapy-induced damage to the ovarian environment.

Francesca E Duncan1, Bruce F Kimler2, Shawn M Briley1.   

Abstract

Entities:  

Keywords:  fertility preservation; mitigation; ovary; protection; radiation

Mesh:

Year:  2016        PMID: 27117319      PMCID: PMC5549657          DOI: 10.2217/fon-2016-0121

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.404


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2.  In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates.

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4.  More harm than good? The anatomy of misguided shielding of the ovaries.

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Review 5.  Pharmacologic approaches to radiation protection.

Authors:  David M Brizel
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6.  WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability.

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Review 8.  Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients.

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Review 9.  Toxicity of chemotherapy and radiation on female reproduction.

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10.  Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.

Authors:  W Qiu; B Leibowitz; L Zhang; J Yu
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Review 1.  Pharmacological management of ionizing radiation injuries: current and prospective agents and targeted organ systems.

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2.  Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibrosis in the nonhuman primate†.

Authors:  Farners Amargant; Sharrón L Manuel; Megan J Larmore; Brian W Johnson; Maralee Lawson; Michele T Pritchard; Mary B Zelinski; Francesca E Duncan
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Review 3.  Unlaid Eggs: Ovarian Damage after Low-Dose Radiation.

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4.  Premature Ovarian Insufficiency (POI) Induced by Dynamic Intensity Modulated Radiation Therapy via P13K-AKT-FOXO3a in Rat Models.

Authors:  Lianli He; Xiaoqin Long; Nixiao Yu; Yajun Li; Xiaoyun Liu; Xiaoju Cheng
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5.  Use of a Small Animal Radiation Research Platform (SARRP) facilitates analysis of systemic versus targeted radiation effects in the mouse ovary.

Authors:  Allison R Grover; Bruce F Kimler; Francesca E Duncan
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