Dawn M Elfenbein1, Micah Katz2, David F Schneider2, Herbert Chen2, Rebecca S Sippel2. 1. University of Wisconsin, Department of Surgery, Section of Endocrine Surgery, 600 Highland Ave, K4/739, Madison, WI 53792. Electronic address: delfenbe@uci.edu. 2. University of Wisconsin, Department of Surgery, Section of Endocrine Surgery, 600 Highland Ave, K4/739, Madison, WI 53792.
Abstract
BACKGROUND: The utilization of thyroidectomy for Graves' disease remains controversial; we aim to evaluate the indications for and complications of thyroidectomy for Graves' in children. METHODS: A retrospective analysis was performed on all Graves' patients who underwent thyroidectomy from 2009 to 2013 at a high volume academic center. Pediatric patients were <18years old, and a comparative analysis of indications for surgery and complications was performed. RESULTS: 167 patients underwent thyroidectomy: 31 pediatric patients and 136 adults. Failure of antithyroid medications was the indication for surgery in 55% of the children vs 36% of adults (p=0.05). Mean duration of medications prior to surgery was similar. No children had failed RAI therapy prior to surgery, but 12.5% of the adult population had (p=0.04). Surgical outcomes were similar. CONCLUSION: Clinicians may be more likely to refer children who fail medical treatment to surgery over RAI. Thyroidectomy at a high volume hospital should be discussed as a treatment option for children with Graves'.
BACKGROUND: The utilization of thyroidectomy for Graves' disease remains controversial; we aim to evaluate the indications for and complications of thyroidectomy for Graves' in children. METHODS: A retrospective analysis was performed on all Graves' patients who underwent thyroidectomy from 2009 to 2013 at a high volume academic center. Pediatric patients were <18years old, and a comparative analysis of indications for surgery and complications was performed. RESULTS: 167 patients underwent thyroidectomy: 31 pediatric patients and 136 adults. Failure of antithyroid medications was the indication for surgery in 55% of the children vs 36% of adults (p=0.05). Mean duration of medications prior to surgery was similar. No children had failed RAI therapy prior to surgery, but 12.5% of the adult population had (p=0.04). Surgical outcomes were similar. CONCLUSION: Clinicians may be more likely to refer children who fail medical treatment to surgery over RAI. Thyroidectomy at a high volume hospital should be discussed as a treatment option for children with Graves'.
Authors: Rebecca S Bahn Chair; Henry B Burch; David S Cooper; Jeffrey R Garber; M Carol Greenlee; Irwin Klein; Peter Laurberg; I Ross McDougall; Victor M Montori; Scott A Rivkees; Douglas S Ross; Julie Ann Sosa; Marius N Stan Journal: Thyroid Date: 2011-04-21 Impact factor: 6.568
Authors: Rebecca S Bahn; Henry S Burch; David S Cooper; Jeffrey R Garber; Carol M Greenlee; Irwin L Klein; Peter Laurberg; I Ross McDougall; Scott A Rivkees; Douglas Ross; Julie Ann Sosa; Marius N Stan Journal: Thyroid Date: 2009-07 Impact factor: 6.568
Authors: Jonathan Sherman; Geoffrey B Thompson; Aida Lteif; W Frederick Schwenk; Jon van Heerden; David R Farley; Seema Kumar; Donald Zimmerman; Marilyn Churchward; Clive S Grant Journal: Surgery Date: 2006-11-01 Impact factor: 3.982
Authors: Sarah C Oltmann; Andrew V Brekke; David F Schneider; Sarah C Schaefer; Herbert Chen; Rebecca S Sippel Journal: Ann Surg Oncol Date: 2014-09-12 Impact factor: 5.344
Authors: David F Schneider; Philip E Sonderman; Michaela F Jones; Kristin A Ojomo; Herbert Chen; Juan C Jaume; Diane F Elson; Scott B Perlman; Rebecca S Sippel Journal: Ann Surg Oncol Date: 2014-07-08 Impact factor: 5.344
Authors: Dawn M Elfenbein; David F Schneider; Jeffrey Havlena; Herbert Chen; Rebecca S Sippel Journal: Ann Surg Oncol Date: 2014-09-23 Impact factor: 5.344
Authors: Annabel S Zaat; Joep P M Derikx; Nitash Zwaveling-Soonawala; A S Paul van Trotsenburg; Christiaan F Mooij Journal: Eur Thyroid J Date: 2020-11-17