Literature DB >> 27112355

Trends in epidemiology and hospitalization utilization for myelomeningocele repair from 2000 to 2009.

Dominic A Harris1,2, Jacob Cherian1,2, Melissa LoPresti1,2, Andrew Jea1,2, Sandi Lam3,4.   

Abstract

PURPOSE: Although the incidence of myelomeningocele (MMC) has declined over the past decades with folic acid supplementation and prenatal screening, neural tube defects remain the most common birth defect in the USA. A majority of affected neonates require surgical repair. To characterize US trends in the epidemiology and hospital utilization of MMC repair over the past decade, we analyzed a nationally representative database.
METHODS: We queried the Healthcare Cost and Utilization Project (HCUP) Kid's Inpatient Database (KID) for all discharges with procedure code for MMC repair for the years 2000, 2003, 2006, and 2009. The cohorts from these time points were compared for their demographic and in-hospital variables. Results are reported as estimated frequencies and means with 95 % confidence intervals (CI).
RESULTS: Sex, race, insurance status, family income level, and mortality of affected infants have not changed significantly over the decade. A majority of neonatal MMC repairs occur in larger hospital bed size and more specialized children's hospital centers. Of patients, 52.3 to 60 % receive VPS placement during the same admission as the primary MMC repair. Total hospital costs for the MMC hospitalizations have remained relatively stable from 42,843 dollars in 2003 to 46,749 dollars in 2009 (adjusted to 2009 dollars).
CONCLUSION: Demographics of children having MMC repair have not changed significantly over the past decade, while these surgeries have become more concentrated in pediatric-specialized centers. There appears to be a plateau in public health and access advances with relatively stable cost of MMC hospital care.

Entities:  

Keywords:  Epidemiology; Myelomeningocele; Neural tube defect; Spina bifida

Mesh:

Year:  2016        PMID: 27112355     DOI: 10.1007/s00381-016-3091-5

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  21 in total

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2.  Decline in the prevalence of spina bifida and anencephaly by race/ethnicity: 1995-2002.

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Review 4.  Cultural considerations in the care of children with spina bifida.

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Journal:  Pediatr Clin North Am       Date:  2010-08       Impact factor: 3.278

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Authors:  N Scott Adzick; Elizabeth A Thom; Catherine Y Spong; John W Brock; Pamela K Burrows; Mark P Johnson; Lori J Howell; Jody A Farrell; Mary E Dabrowiak; Leslie N Sutton; Nalin Gupta; Noel B Tulipan; Mary E D'Alton; Diana L Farmer
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6.  Maternal ethnicity and risk of neural tube defects: a population-based study.

Authors:  Joel G Ray; Marian J Vermeulen; Chris Meier; David E C Cole; Philip R Wyatt
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9.  Surgical treatment of myelomeningocele: year 2000 hospitalization, outcome, and cost analysis in the US.

Authors:  Anthony H Sin; Mahmoud Rashidi; Gloria Caldito; Anil Nanda
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  2 in total

1.  In utero repair of fetal rat myelomeningocele affects neuromuscular development in the bladder.

Authors:  Liangfeng Tang; Haijun Zhong; Hong Chen; Jian Shen; Yunli Bi; Xianmin Xiao
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2.  Myelomeningocele: need for long-time complex follow-up-an observational study.

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  2 in total

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