Literature DB >> 18447669

Toward reducing shunt placement rates in patients with myelomeningocele.

Aabir Chakraborty1, Darach Crimmins, Richard Hayward, Dominic Thompson.   

Abstract

OBJECT: The prevalence of shunt-dependent hydrocephalus in patients with myelomeningocele has been reported to be in the region of 85%, and shunt-related complications are a significant cause of morbidity and mortality in these patients. Since 1997 the authors have adopted a stringent policy with respect to shunt placement in patients with myelomeningocele, reserving this treatment for those with symptomatic hydrocephalus, severe ventricular dilation at the time of presentation, and/or unequivocal progressive ventriculomegaly after primary closure. They report their experience.
METHODS: The authors reviewed all cases of myelomeningocele involving patients who presented to their institution over a 10-year period. They excluded cases in which the primary closure was carried out at another institution or in which there was not at least 12 months of clinical and imaging follow-up. Data regarding shunt insertion shunt-related complications, and clinical outcome were obtained from a review of the clinical records and analyzed.
RESULTS: Fifty-four cases satisfied the inclusion criteria for this study. Shunt insertion was performed in 28 of these cases (51.9%).
CONCLUSIONS: Applying more stringent guidelines for shunt placement, permitting moderate ventricular dilation, and accepting some mild increase in ventricular size after myelomeningocele closure has resulted in a reduced rate of shunt placement compared with previous series. The rate is comparable to that reported following in utero closure of myelomeningocele.

Entities:  

Mesh:

Year:  2008        PMID: 18447669     DOI: 10.3171/PED/2008/1/5/361

Source DB:  PubMed          Journal:  J Neurosurg Pediatr        ISSN: 1933-0707            Impact factor:   2.375


  22 in total

Review 1.  The changing incidence of myelomeningocele and its impact on pediatric neurosurgery: a review from the Children's Memorial Hospital.

Authors:  Robin M Bowman; Vanda Boshnjaku; David G McLone
Journal:  Childs Nerv Syst       Date:  2009-03-27       Impact factor: 1.475

Review 2.  Who needs surgery for pediatric myelomeningocele? A retrospective study and literature review.

Authors:  Humberto Marreiros; Clara Loff; Eulália Calado
Journal:  J Spinal Cord Med       Date:  2014-07-16       Impact factor: 1.985

Review 3.  Myelomeningocele: the management of the associated hydrocephalus.

Authors:  G Tamburrini; P Frassanito; K Iakovaki; F Pignotti; C Rendeli; D Murolo; C Di Rocco
Journal:  Childs Nerv Syst       Date:  2013-09-07       Impact factor: 1.475

Review 4.  Care for Adults with Spina Bifida: Current State and Future Directions.

Authors:  Shubhra Mukherjee; Jacqueline Pasulka
Journal:  Top Spinal Cord Inj Rehabil       Date:  2017

5.  Rate of shunt revision as a function of age in patients with shunted hydrocephalus due to myelomeningocele.

Authors:  Esther B Dupepe; Betsy Hopson; James M Johnston; Curtis J Rozzelle; W Jerry Oakes; Jeffrey P Blount; Brandon G Rocque
Journal:  Neurosurg Focus       Date:  2016-11       Impact factor: 4.047

Review 6.  Hydrocephalus associated with neural tube defects: characteristics, management, and outcome in sub-Saharan Africa.

Authors:  Benjamin C Warf
Journal:  Childs Nerv Syst       Date:  2011-09-17       Impact factor: 1.475

7.  Motor contingency learning and infants with Spina Bifida.

Authors:  Heather B Taylor; Marcia A Barnes; Susan H Landry; Paul Swank; Jack M Fletcher; Furong Huang
Journal:  J Int Neuropsychol Soc       Date:  2013-01-08       Impact factor: 2.892

8.  First 60 fetal in-utero myelomeningocele repairs at Saint Louis Fetal Care Institute in the post-MOMS trial era: hydrocephalus treatment outcomes (endoscopic third ventriculostomy versus ventriculo-peritoneal shunt).

Authors:  Samer K Elbabaa; Anne M Gildehaus; Matthew J Pierson; J Andrew Albers; Emanuel J Vlastos
Journal:  Childs Nerv Syst       Date:  2017-05-03       Impact factor: 1.475

9.  Cognitive and functional outcome in spina bifida-Chiari II malformation.

Authors:  Michael D Jenkinson; Sophie Campbell; Caroline Hayhurst; Simon Clark; Jothy Kandasamy; Maggie K Lee; Ann Flynn; Peter Murphy; Conor L Mallucci
Journal:  Childs Nerv Syst       Date:  2010-12-31       Impact factor: 1.475

10.  Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement.

Authors:  Noel Tulipan; John C Wellons; Elizabeth A Thom; Nalin Gupta; Leslie N Sutton; Pamela K Burrows; Diana Farmer; William Walsh; Mark P Johnson; Larry Rand; Susan Tolivaisa; Mary E D'alton; N Scott Adzick
Journal:  J Neurosurg Pediatr       Date:  2015-09-15       Impact factor: 2.375

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.