Grégoire Massoullié1, Jérome Wintzer-Wehekind1, Chouki Chenaf2, Aurélien Mulliez3, Bruno Pereira3, Nicolas Authier2, Alain Eschalier2, Guillaume Clerfond1, Géraud Souteyrand1, Simon Tabassome4, Nicolas Danchin5, Bernard Citron1, Jean-René Lusson1, Étienne Puymirat5, Pascal Motreff1, Romain Eschalier6. 1. UMR 6284, cardiovascular interventional therapy and imaging (CaVITI), image science for interventional techniques (ISIT), université de Clermont, université d'Auvergne, 63000 Clermont-Ferrand, France; Cardiology department, Clermont university hospital, 58, rue Montalembert, 63000 Clermont-Ferrand, France. 2. Pharmacology department, CHU of Clermont-Ferrand, 63000 Clermont-Ferrand, France. 3. Biostatistics unit, clinical research and innovation delegation, CHU of Clermont-Ferrand, 63000 Clermont-Ferrand, France. 4. Inserm, U-698, UPMC-Paris 6, clinical research unit (URC)-Est, hospital Saint-Antoine, AP-HP, 75012 Paris, France. 5. Inserm U-970, department of cardiology, European hospital of Georges-Pompidou, university Paris Descartes, AP-HP, 75015 Paris, France. 6. UMR 6284, cardiovascular interventional therapy and imaging (CaVITI), image science for interventional techniques (ISIT), université de Clermont, université d'Auvergne, 63000 Clermont-Ferrand, France; Cardiology department, Clermont university hospital, 58, rue Montalembert, 63000 Clermont-Ferrand, France. Electronic address: reschalier@chu-clermontferrand.fr.
Abstract
BACKGROUND: Multicentre registries of myocardial infarction management show a steady improvement in prognosis and greater access to myocardial revascularization in a more timely manner. While French registries are the standard references, the question arises: are data stemming solely from the activity of French cardiac intensive care units (ICUs) a true reflection of the entire French population with ST-segment elevation myocardial infarction (STEMI)? AIM: To compare data on patients hospitalized for STEMI from two French registries: the French registry of acute ST-elevation or non-ST-elevation myocardial infarction (FAST-MI) and the Échantillon généraliste des bénéficiaires (EGB) database. METHODS: We compared patients treated for STEMI listed in the FAST-MI 2010 registry (n=1716) with those listed in the EGB database, which comprises a sample of 1/97th of the French population, also from 2010 (n=403). RESULTS: Compared with the FAST-MI 2010 registry, the EGB database population were older (67.2±15.3 vs 63.3±14.5 years; P<0.001), had a higher percentage of women (36.0% vs 24.7%; P<0.001), were less likely to undergo emergency coronary angiography (75.2% vs 96.3%; P<0.001) and were less often treated in university hospitals (27.1% vs 37.0%; P=0.001). There were no significant differences between the two registries in terms of cardiovascular risk factors, comorbidities and drug treatment at admission. Thirty-day mortality was higher in the EGB database (10.2% vs 4.4%; P<0.001). CONCLUSIONS: Registries such as FAST-MI are indispensable, not only for assessing epidemiological changes over time, but also for evaluating the prognostic effect of modern STEMI management. Meanwhile, exploitation of data from general databases, such as EGB, provides additional relevant information, as they include a broader population not routinely admitted to cardiac ICUs.
BACKGROUND: Multicentre registries of myocardial infarction management show a steady improvement in prognosis and greater access to myocardial revascularization in a more timely manner. While French registries are the standard references, the question arises: are data stemming solely from the activity of French cardiac intensive care units (ICUs) a true reflection of the entire French population with ST-segment elevation myocardial infarction (STEMI)? AIM: To compare data on patients hospitalized for STEMI from two French registries: the French registry of acute ST-elevation or non-ST-elevation myocardial infarction (FAST-MI) and the Échantillon généraliste des bénéficiaires (EGB) database. METHODS: We compared patients treated for STEMI listed in the FAST-MI 2010 registry (n=1716) with those listed in the EGB database, which comprises a sample of 1/97th of the French population, also from 2010 (n=403). RESULTS: Compared with the FAST-MI 2010 registry, the EGB database population were older (67.2±15.3 vs 63.3±14.5 years; P<0.001), had a higher percentage of women (36.0% vs 24.7%; P<0.001), were less likely to undergo emergency coronary angiography (75.2% vs 96.3%; P<0.001) and were less often treated in university hospitals (27.1% vs 37.0%; P=0.001). There were no significant differences between the two registries in terms of cardiovascular risk factors, comorbidities and drug treatment at admission. Thirty-day mortality was higher in the EGB database (10.2% vs 4.4%; P<0.001). CONCLUSIONS: Registries such as FAST-MI are indispensable, not only for assessing epidemiological changes over time, but also for evaluating the prognostic effect of modern STEMI management. Meanwhile, exploitation of data from general databases, such as EGB, provides additional relevant information, as they include a broader population not routinely admitted to cardiac ICUs.
Authors: A Burgun; E Bernal-Delgado; W Kuchinke; T van Staa; J Cunningham; E Lettieri; C Mazzali; D Oksen; F Estupiñan; A Barone; G Chène Journal: Yearb Med Inform Date: 2017-09-11
Authors: Benjamin Duband; Pascal Motreff; Pierre Marcollet; Alexandre Gamet; Marie-Pascale Decomis; Olivier Bar; Christophe Saint Etienne; Radwan Hakim; Alexandre Canville; Louis Viallard; Farzin BeyguI; Pierre Francois Lesault; Philippe Bonnet; Eric Durand; Emmanuel Boiffard; Jean-Philippe Collet; Hakim Benamer; Philippe Commeau; Guillaume Cayla; Bruno Pereira; Rene Koning; Gregoire Rangé Journal: Medicine (Baltimore) Date: 2022-09-02 Impact factor: 1.817