Literature DB >> 27104219

Discovering Biomarkers within the Genomic Landscape of Renal Cell Carcinoma.

Sankin A1.   

Abstract

Recent advances in molecular sequencing technology have led to the discovery of numerous biomarkers in renal cell carcinoma (RCC). These biomarkers have the potential to predict clinical outcomes and aid in clinical management decisions. The following commentary is a review of the preliminary data on some of the most promising genetic biomarker candidates.

Entities:  

Keywords:  Biomarker; Genomics; Renal cell carcinoma

Year:  2016        PMID： 27104219      PMCID： PMC4836862          DOI： 10.4172/jok.1000115

Source DB:  PubMed          Journal:  J Kidney


  12 in total

Review 1.  The role of surgery in the management of early-stage renal cancer.

Authors:  Paul Russo
Journal:  Hematol Oncol Clin North Am       Date:  2011-06-16       Impact factor: 3.722

2.  Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.

Authors:  Guangwu Guo; Yaoting Gui; Shengjie Gao; Aifa Tang; Xueda Hu; Yi Huang; Wenlong Jia; Zesong Li; Minghui He; Liang Sun; Pengfei Song; Xiaojuan Sun; Xiaokun Zhao; Sangming Yang; Chaozhao Liang; Shengqing Wan; Fangjian Zhou; Chao Chen; Jialou Zhu; Xianxin Li; Minghan Jian; Liang Zhou; Rui Ye; Peide Huang; Jing Chen; Tao Jiang; Xiao Liu; Yong Wang; Jing Zou; Zhimao Jiang; Renhua Wu; Song Wu; Fan Fan; Zhongfu Zhang; Lin Liu; Ruilin Yang; Xingwang Liu; Haibo Wu; Weihua Yin; Xia Zhao; Yuchen Liu; Huanhuan Peng; Binghua Jiang; Qingxin Feng; Cailing Li; Jun Xie; Jingxiao Lu; Karsten Kristiansen; Yingrui Li; Xiuqing Zhang; Songgang Li; Jian Wang; Huanming Yang; Zhiming Cai; Jun Wang
Journal:  Nat Genet       Date:  2011-12-04       Impact factor: 38.330

3.  Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research network.

Authors:  A Ari Hakimi; Irina Ostrovnaya; Boris Reva; Nikolaus Schultz; Ying-Bei Chen; Mithat Gonen; Han Liu; Shugaku Takeda; Martin H Voss; Satish K Tickoo; Victor E Reuter; Paul Russo; Emily H Cheng; Chris Sander; Robert J Motzer; James J Hsieh
Journal:  Clin Cancer Res       Date:  2013-04-25       Impact factor: 12.531

4.  Clinical and pathologic impact of select chromatin-modulating tumor suppressors in clear cell renal cell carcinoma.

Authors:  A Ari Hakimi; Ying-Bei Chen; James Wren; Mithat Gonen; Omar Abdel-Wahab; Adriana Heguy; Han Liu; Shugaku Takeda; Satish K Tickoo; Victor E Reuter; Martin H Voss; Robert J Motzer; Jonathan A Coleman; Emily H Cheng; Paul Russo; James J Hsieh
Journal:  Eur Urol       Date:  2012-09-27       Impact factor: 20.096

5.  Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation.

Authors:  Payal Kapur; Samuel Peña-Llopis; Alana Christie; Leah Zhrebker; Andrea Pavía-Jiménez; W Kimryn Rathmell; Xian-Jin Xie; James Brugarolas
Journal:  Lancet Oncol       Date:  2013-01-16       Impact factor: 41.316

6.  A clear picture of renal cell carcinoma.

Authors:  A Ari Hakimi; Can G Pham; James J Hsieh
Journal:  Nat Genet       Date:  2013-08       Impact factor: 38.330

7.  Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy.

Authors:  Martin H Voss; A Ari Hakimi; Can G Pham; A Rose Brannon; Ying-Bei Chen; Luis F Cunha; Oguz Akin; Han Liu; Shugaku Takeda; Sasinya N Scott; Nicholas D Socci; Agnes Viale; Nikolaus Schultz; Chris Sander; Victor E Reuter; Paul Russo; Emily H Cheng; Robert J Motzer; Michael F Berger; James J Hsieh
Journal:  Clin Cancer Res       Date:  2014-03-12       Impact factor: 12.531

8.  Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.

Authors:  Marco Gerlinger; Andrew J Rowan; Stuart Horswell; James Larkin; David Endesfelder; Eva Gronroos; Pierre Martinez; Nicholas Matthews; Aengus Stewart; Charles Swanton; M Math; Patrick Tarpey; Ignacio Varela; Benjamin Phillimore; Sharmin Begum; Neil Q McDonald; Adam Butler; David Jones; Keiran Raine; Calli Latimer; Claudio R Santos; Mahrokh Nohadani; Aron C Eklund; Bradley Spencer-Dene; Graham Clark; Lisa Pickering; Gordon Stamp; Martin Gore; Zoltan Szallasi; Julian Downward; P Andrew Futreal
Journal:  N Engl J Med       Date:  2012-03-08       Impact factor: 91.245

9.  Comprehensive molecular characterization of clear cell renal cell carcinoma.

Authors: 
Journal:  Nature       Date:  2013-06-23       Impact factor: 49.962

10.  The impact of genetic heterogeneity on biomarker development in kidney cancer assessed by multiregional sampling.

Authors:  Alexander Sankin; Abraham A Hakimi; Nina Mikkilineni; Irina Ostrovnaya; Mikhail T Silk; Yupu Liang; Roy Mano; Michael Chevinsky; Robert J Motzer; Stephen B Solomon; Emily H Cheng; Jeremy C Durack; Jonathan A Coleman; Paul Russo; James J Hsieh
Journal:  Cancer Med       Date:  2014-08-14       Impact factor: 4.452
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  1 in total

1.  Characterization of Ageing- and Diet-Related Swine Models of Sarcopenia and Sarcopenic Obesity.

Authors:  Consolacion Garcia-Contreras; Marta Vazquez-Gomez; Laura Torres-Rovira; Jorge Gonzalez; Esteban Porrini; Magali Gonzalez-Colaço; Beatriz Isabel; Susana Astiz; Antonio Gonzalez-Bulnes
Journal:  Int J Mol Sci       Date:  2018-03-12       Impact factor: 5.923
  1 in total

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