Literature DB >> 27100935

B-Raf activation loop phosphorylation revisited.

Martin Köhler1,2,3, Tilman Brummer1,4,5.   

Abstract

Entities:  

Keywords:  BRAF fusion oncogene; dimer; phosphorylation; protein-protein interaction

Mesh：

Substances：

Year:  2016        PMID： 27100935      PMCID： PMC4889292          DOI： 10.1080/15384101.2016.1159111

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  Regulation of RAF protein kinases in ERK signalling.

Authors:  Hugo Lavoie; Marc Therrien
Journal:  Nat Rev Mol Cell Biol       Date:  2015-05       Impact factor: 94.444

Review 2.  Alike but Different: RAF Paralogs and Their Signaling Outputs.

Authors:  Enrico Desideri; Anna Lina Cavallo; Manuela Baccarini
Journal:  Cell       Date:  2015-05-21       Impact factor: 41.582

3.  Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling.

Authors:  Michael Röring; Ricarda Herr; Gina J Fiala; Katharina Heilmann; Sandra Braun; Anja E Eisenhardt; Sebastian Halbach; David Capper; Andreas von Deimling; Wolfgang W Schamel; Darren N Saunders; Tilman Brummer
Journal:  EMBO J       Date:  2012-04-17       Impact factor: 11.598

4.  Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.

Authors:  B H Zhang; K L Guan
Journal:  EMBO J       Date:  2000-10-16       Impact factor: 11.598

5.  Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas.

Authors:  Angela J Sievert; Shih-Shan Lang; Katie L Boucher; Peter J Madsen; Erin Slaunwhite; Namrata Choudhari; Meghan Kellet; Phillip B Storm; Adam C Resnick
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-26       Impact factor: 11.205

6.  Activation loop phosphorylation regulates B-Raf in vivo and transformation by B-Raf mutants.

Authors:  Martin Köhler; Michael Röring; Björn Schorch; Katharina Heilmann; Natalie Stickel; Gina J Fiala; Lisa C Schmitt; Sandra Braun; Sophia Ehrenfeld; Franziska M Uhl; Thorsten Kaltenbacher; Florian Weinberg; Sebastian Herzog; Robert Zeiser; Wolfgang W Schamel; Hassan Jumaa; Tilman Brummer
Journal:  EMBO J       Date:  2015-12-10       Impact factor: 11.598

7.  Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.

Authors:  Sonja J Heidorn; Carla Milagre; Steven Whittaker; Arnaud Nourry; Ion Niculescu-Duvas; Nathalie Dhomen; Jahan Hussain; Jorge S Reis-Filho; Caroline J Springer; Catrin Pritchard; Richard Marais
Journal:  Cell       Date:  2010-01-22       Impact factor: 41.582
  7 in total
  10 in total

1.  Activation of SnRK2 by Raf-like kinase ARK represents a primary mechanism of ABA and abiotic stress responses.

Authors:  Mousona Islam; Takumi Inoue; Mayuka Hiraide; Nobiza Khatun; Akida Jahan; Keiko Kuwata; Sotaro Katagiri; Taishi Umezawa; Izumi Yotsui; Yoichi Sakata; Daisuke Takezawa
Journal:  Plant Physiol       Date:  2021-03-15       Impact factor: 8.340

Review 2.  Minor structural changes, major functional impacts: posttranslational modifications and drug targets.

Authors:  Hyo Jung Kim
Journal:  Arch Pharm Res       Date:  2022-10-17       Impact factor: 6.010

Review 3.  Advances towards Understanding the Mechanism of Action of the Hsp90 Complex.

Authors:  Chrisostomos Prodromou; Dennis M Bjorklund
Journal:  Biomolecules       Date:  2022-04-19

4.  B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model.

Authors:  Thomas Reinheckel; Tilman Brummer; Martin Köhler; Sophia Ehrenfeld; Sebastian Halbach; Manuel Lauinger; Ulrike Burk; Nadine Reischmann; Shuofei Cheng; Corinna Spohr; Franziska Maria Uhl; Natalie Köhler; Kathrin Ringwald; Sandra Braun; Christoph Peters; Robert Zeiser
Journal:  Oncogene       Date:  2019-01-18       Impact factor: 8.756

5.  K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling.

Authors:  Qing Yin; Tao Han; Bin Fang; Guolin Zhang; Chao Zhang; Evan R Roberts; Victoria Izumi; Mengmeng Zheng; Shulong Jiang; Xiu Yin; Minjung Kim; Jianfeng Cai; Eric B Haura; John M Koomen; Keiran S M Smalley; Lixin Wan
Journal:  Nat Commun       Date:  2019-04-23       Impact factor: 14.919

6.  The mechanism of Raf activation through dimerization.

Authors:  Mingzhen Zhang; Ryan Maloney; Hyunbum Jang; Ruth Nussinov
Journal:  Chem Sci       Date:  2021-11-18       Impact factor: 9.825

7.  Recognition of BRAF by CDC37 and Re-Evaluation of the Activation Mechanism for the Class 2 BRAF-L597R Mutant.

Authors:  Dennis M Bjorklund; R Marc L Morgan; Jasmeen Oberoi; Katie L I M Day; Panagiota A Galliou; Chrisostomos Prodromou
Journal:  Biomolecules       Date:  2022-06-28

Review 8.  The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy.

Authors:  Jimin Yuan; Xiaoduo Dong; Jiajun Yap; Jiancheng Hu
Journal:  J Hematol Oncol       Date:  2020-08-17       Impact factor: 17.388

9.  De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens.

Authors:  Wei He; Liang Zhang; Oscar D Villarreal; Rongjie Fu; Ella Bedford; Jingzhuang Dou; Anish Y Patel; Mark T Bedford; Xiaobing Shi; Taiping Chen; Blaine Bartholomew; Han Xu
Journal:  Nat Commun       Date:  2019-10-04       Impact factor: 14.919

Review 10.  Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy.

Authors:  Ufuk Degirmenci; Mei Wang; Jiancheng Hu
Journal:  Cells       Date:  2020-01-13       Impact factor: 6.600
  10 in total

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