Literature DB >> 27099752

Giant neck swelling.

Utpal De1, Mintu Mohon Nandi1, Pranoy Kabiraj1.   

Abstract

The most common benign salivary gland tumor is pleomorphic adenoma. They can attain giant proportions and weigh several kilograms. They can cause facial disfigurement and, if untreated, could lead malignant transformation. This image depicts a 7.5 kg pleomorphic adenoma of right submandibular gland with malignant change in a 55-year-old male.

Entities:  

Keywords:  Carcinoma ex pleomorphic adenoma; giant pleomorphic adenoma; submandibular tumor

Year:  2016        PMID: 27099752      PMCID: PMC4831408          DOI: 10.1002/ccr3.490

Source DB:  PubMed          Journal:  Clin Case Rep        ISSN: 2050-0904


Quiz

A 55‐year‐old man presented with a giant, firm, nontender neck swelling insidiously growing since 40 years. His only complain was facial disfigurement. What is your probable diagnosis? Thyroid mass Lymphoma Cystic hygroma Submandibular tumor

Legend of Snap‐Shot

A 55‐year‐old man presented with a huge, firm, nontender neck swelling (28 × 25 × 17 cm) and facial disfigurement (Fig. 1). The swelling rapidly increased in size over the past three months with ulceration and bleeding from the advancing “apex”. Fine‐needle aspiration cytology was consistent with pleomophic salivary adenoma. Computerized tomography (Fig. 2) suggested it to be a mass arising from right submandibular gland. The mass was excised under general anesthesia. It weighed 7.5 kg. Postoperative recovery was uneventful. Histopathology revealed carcinoma ex‐pleomorphic adenoma with sarcomatous differentiation. Pleomorphic salivary adenomas are most common neoplasm of major salivary glands 1. Six percent show transformation to carcinoma 2. Sarcomatous degeneration is rare found in 2.5% 3.
Figure 1

Figure showing giant neck swelling.

Figure 2

CT image depicting the tumor.

Figure showing giant neck swelling. CT image depicting the tumor.

Conflict of Interest

None declared.
  4 in total

1.  A giant pleomorphic adenoma of the submandibular salivary gland: a case report.

Authors:  Colin J Perumal; Mark Meyer; Ashraf Mohamed
Journal:  Craniomaxillofac Trauma Reconstr       Date:  2012-09

2.  Giant presentation of pleomorphic adenoma in major salivary gland.

Authors:  Manish Gupta; Neena Chaudhary; Monica Gupta
Journal:  BMJ Case Rep       Date:  2011-06-30

3.  Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population.

Authors:  Z Tian; L Li; L Wang; Y Hu; J Li
Journal:  Int J Oral Maxillofac Surg       Date:  2009-11-29       Impact factor: 2.789

4.  Giant neck swelling.

Authors:  Utpal De; Mintu Mohon Nandi; Pranoy Kabiraj
Journal:  Clin Case Rep       Date:  2016-03-10
  4 in total
  1 in total

1.  Giant neck swelling.

Authors:  Utpal De; Mintu Mohon Nandi; Pranoy Kabiraj
Journal:  Clin Case Rep       Date:  2016-03-10
  1 in total

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