Andreas Detterbeck1, Michael Hofmeister2, Elisabeth Hofmann2, Daniel Haddad3, Daniel Weber3, Astrid Hölzing4, Simon Zabler4, Matthias Schmid5, Karl-Heinz Hiller3, Peter Jakob3, Jens Engel4, Jochen Hiller6, Ursula Hirschfelder2. 1. Department of Orthodontics and Orofacial Orthopedics, University of Erlangen Medical School, Erlangen, Germany. andreas.detterbeck@uk-erlangen.de. 2. Department of Orthodontics and Orofacial Orthopedics, University of Erlangen Medical School, Erlangen, Germany. 3. Research Center for Magnetic Resonance Bavaria (MRB), Würzburg, Germany. 4. Fraunhofer Institute for Integrated Circuits (IIS), Project Group NanoCT Systems, Würzburg, Germany. 5. Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), University of Bonn, Bonn, Germany. 6. Fraunhofer Institute for Integrated Circuits (IIS), Application Center for Computed Tomography in Metrology, Deggendorf, Germany.
Abstract
OBJECTIVES: To examine the relative usefulness and suitability of magnetic resonance imaging (MRI) in daily clinical practice as compared to various technologies of computed tomography (CT) in addressing questions of orthodontic interest. METHODS: Three blinded raters evaluated 2D slices and 3D reconstructions created from scans of two pig heads. Five imaging modalities were used, including three CT technologies-multislice (MSCT), cone-beam CT (CBCT), and industrial (µCT)-and two MRI protocols with different scan durations. Defined orthodontic parameters were rated one by one on the 2D slices and the 3D reconstructions, followed by final overall ratings for each modality. A mixed linear model was used for statistical analysis. RESULTS: Based on the 2D slices, the parameter of visualizing tooth-germ topography did not yield any significantly different ratings for MRI versus any of the CT scans. While some ratings for the other parameters did involve significant differences, how these should be interpreted depends greatly on the relevance of each parameter. Based on the 3D reconstructions, the only significant difference between technologies was noted for the parameter of visualizing root-surface morphology. Based on the final overall ratings, the imaging performance of the standard MRI protocol was noninferior to the performance of the three CT technologies. CONCLUSIONS: On comparing the imaging performance of MRI and CT scans, it becomes clear that MRI has a huge potential for applications in daily clinical practice. Given its additional benefits of a good contrast ratio and complete absence of ionizing radiation, further studies are needed to explore this clinical potential in greater detail.
OBJECTIVES: To examine the relative usefulness and suitability of magnetic resonance imaging (MRI) in daily clinical practice as compared to various technologies of computed tomography (CT) in addressing questions of orthodontic interest. METHODS: Three blinded raters evaluated 2D slices and 3D reconstructions created from scans of two pig heads. Five imaging modalities were used, including three CT technologies-multislice (MSCT), cone-beam CT (CBCT), and industrial (µCT)-and two MRI protocols with different scan durations. Defined orthodontic parameters were rated one by one on the 2D slices and the 3D reconstructions, followed by final overall ratings for each modality. A mixed linear model was used for statistical analysis. RESULTS: Based on the 2D slices, the parameter of visualizing tooth-germ topography did not yield any significantly different ratings for MRI versus any of the CT scans. While some ratings for the other parameters did involve significant differences, how these should be interpreted depends greatly on the relevance of each parameter. Based on the 3D reconstructions, the only significant difference between technologies was noted for the parameter of visualizing root-surface morphology. Based on the final overall ratings, the imaging performance of the standard MRI protocol was noninferior to the performance of the three CT technologies. CONCLUSIONS: On comparing the imaging performance of MRI and CT scans, it becomes clear that MRI has a huge potential for applications in daily clinical practice. Given its additional benefits of a good contrast ratio and complete absence of ionizing radiation, further studies are needed to explore this clinical potential in greater detail.
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