Literature DB >> 27091201

Interaction between education and income on the risk of all-cause mortality: prospective results from the MOLI-SANI study.

Marialaura Bonaccio1, Augusto Di Castelnuovo2, Simona Costanzo2, Mariarosaria Persichillo2, Maria Benedetta Donati2, Giovanni de Gaetano2, Licia Iacoviello2.   

Abstract

OBJECTIVES: To investigate the separate and inter-related associations of education and household income in relation to all-cause mortality.
METHODS: Prospective study on 16,247 men and women (≥35 years), a sub-sample of the MOLI-SANI cohort that had been randomly recruited within an Italian general population. Both education and income were used as categorical variables. Hazard ratios (HR) were calculated by Cox-proportional hazard models.
RESULTS: Over a median follow-up of 7.7 years (125,016 person-years), 694 deaths were ascertained. Either education (HR = 0.68; 95 % CI 0.51-0.91) or income (HR = 0.57; 0.42-0.77) was inversely associated with mortality. After simultaneous adjustment, the association of education appeared to be largely explained by income. A significant interaction between both variables was found (p = 0.0078). The inverse association with mortality was stronger when a higher income was combined with a higher educational level (HR = 0.59; 0.38-0.92 for the highest combination of the two indicators).
CONCLUSIONS: Either education or income was the predictor of mortality in a large sample of the Italian population. The two variables significantly interacted and the inverse association of income with mortality tended to be stronger within higher education groups.

Entities:  

Keywords:  Education; Income; Interaction; Mortality

Mesh:

Year:  2016        PMID: 27091201     DOI: 10.1007/s00038-016-0822-z

Source DB:  PubMed          Journal:  Int J Public Health        ISSN: 1661-8556            Impact factor:   3.380


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