Foong Ming Moy1, Victor Cw Hoe2, Noran Naqiah Hairi1, Shireene Ratna Vethakkan3, Awang Bulgiba1. 1. 1Julius Centre University of Malaya,Department of Social & Preventive Medicine, Faculty of Medicine,University of Malaya,50603 Kuala Lumpur,Malaysia. 2. 2Centre for Occupational and Environmental Health-UM,Department of Social & Preventive Medicine, Faculty of Medicine,University of Malaya,Kuala Lumpur,Malaysia. 3. 3Department of Medicine, Faculty of Medicine,University of Malaya,Kuala Lumpur,Malaysia.
Abstract
OBJECTIVE: To determine the association of vitamin D status with depression and health-related quality of life among women. DESIGN: This was a cross-sectional study conducted among women in Kuala Lumpur, Malaysia. Sociodemographic characteristics, physical activity status, perceived depression and health-related quality of life were assessed via a self-administered questionnaire. Fasting blood samples were taken for the analysis of 25-hydroxyvitamin D, parathyroid hormone, fasting blood glucose and full lipid profile. Complex samples multiple logistic regression analysis was performed. SETTING: Public secondary schools in Kuala Lumpur, Malaysia. SUBJECTS: Seven hundred and seventy female teachers were included. RESULTS: The mean age of participants was 41·15 (95 % CI 40·51, 41·78) years and the majority were ethnic Malays. Over 70 % of them had vitamin D deficiency (<20 ng/ml or <50 nmol/l) and two-thirds were at risk for depression. In the multivariate analysis, ethnic Malays (adjusted OR (aOR)=14·72; 95 % CI 2·12, 102·21) and Indians (aOR=14·02; 95 % CI 2·27, 86·59), those at risk for depression (aOR=1·88, 95 % CI 1·27, 2·79) and those with higher parathyroid hormone level (aOR=1·13; 95 % CI 1·01, 1·26) were associated with vitamin D deficiency, while vitamin D deficiency was negatively associated with mental health-related quality of life (Mental Component Summary) scores (aOR=0·98; 95 % CI 0·97, 0·99). CONCLUSIONS: Vitamin D deficiency is significantly associated with depression and mental health-related quality of life among women in Kuala Lumpur, Malaysia.
OBJECTIVE: To determine the association of vitamin D status with depression and health-related quality of life among women. DESIGN: This was a cross-sectional study conducted among women in Kuala Lumpur, Malaysia. Sociodemographic characteristics, physical activity status, perceived depression and health-related quality of life were assessed via a self-administered questionnaire. Fasting blood samples were taken for the analysis of 25-hydroxyvitamin D, parathyroid hormone, fasting blood glucose and full lipid profile. Complex samples multiple logistic regression analysis was performed. SETTING: Public secondary schools in Kuala Lumpur, Malaysia. SUBJECTS: Seven hundred and seventy female teachers were included. RESULTS: The mean age of participants was 41·15 (95 % CI 40·51, 41·78) years and the majority were ethnic Malays. Over 70 % of them had vitamin D deficiency (<20 ng/ml or <50 nmol/l) and two-thirds were at risk for depression. In the multivariate analysis, ethnic Malays (adjusted OR (aOR)=14·72; 95 % CI 2·12, 102·21) and Indians (aOR=14·02; 95 % CI 2·27, 86·59), those at risk for depression (aOR=1·88, 95 % CI 1·27, 2·79) and those with higher parathyroid hormone level (aOR=1·13; 95 % CI 1·01, 1·26) were associated with vitamin D deficiency, while vitamin D deficiency was negatively associated with mental health-related quality of life (Mental Component Summary) scores (aOR=0·98; 95 % CI 0·97, 0·99). CONCLUSIONS:Vitamin D deficiency is significantly associated with depression and mental health-related quality of life among women in Kuala Lumpur, Malaysia.
Entities:
Keywords:
Depression; Quality of life; Tropical country; Vitamin D deficiency; Women
Authors: Kok-Yong Chin; Nie Yen Low; Wan Ilma Dewiputri; Soelaiman Ima-Nirwanaa Journal: Int J Environ Res Public Health Date: 2017-07-06 Impact factor: 3.390
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