Literature DB >> 27082125

A Theranostic Two-Tone Luminescent PhotoCORM Derived from Re(I) and (2-Pyridyl)-benzothiazole: Trackable CO Delivery to Malignant Cells.

Samantha J Carrington1, Indranil Chakraborty1, Jenna M L Bernard2, Pradip K Mascharak1.   

Abstract

A Re(I) carbonyl complex derived from 2-(2-pyridyl)-benzothiazole (pbt), [Re(H2O)(CO)3(pbt)](CF3SO3) (1), rapidly releases CO under low-power UV illumination. CO photorelease from 1 is accompanied by a change in luminescence from orange to deep blue. These two distinct luminescence signals have been successfully employed to track (a) the entry of the pro-drug 1 into cancer cells and (b) the end of the CO (drug) delivery step within the target.

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Year:  2016        PMID： 27082125     DOI： 10.1021/acs.inorgchem.6b00511

Source DB:  PubMed          Journal:  Inorg Chem        ISSN： 0020-1669            Impact factor:   5.165


  11 in total

1.  Affinity-Enhanced Luminescent Re(I)- and Ru(II)-Based Inhibitors of the Cysteine Protease Cathepsin L.

Authors:  Matthew Huisman; Jacob P Kodanko; Karan Arora; Mackenzie Herroon; Marim Alnaed; John Endicott; Izabela Podgorski; Jeremy J Kodanko
Journal:  Inorg Chem       Date:  2018-06-08       Impact factor: 5.165

2.  Photoactivated in Vitro Anticancer Activity of Rhenium(I) Tricarbonyl Complexes Bearing Water-Soluble Phosphines.

Authors:  Sierra C Marker; Samantha N MacMillan; Warren R Zipfel; Zhi Li; Peter C Ford; Justin J Wilson
Journal:  Inorg Chem       Date:  2018-01-11       Impact factor: 5.165

3.  Tracking CO release in cells via the luminescence of donor molecules and/or their by-products.

Authors:  Tatiana Soboleva; Lisa M Berreau
Journal:  Isr J Chem       Date:  2019-02-11       Impact factor: 3.333

4.  Luminescent Re(I) Carbonyl Complexes as Trackable PhotoCORMs for CO delivery to Cellular Targets.

Authors:  Indranil Chakraborty; Jorge Jimenez; W M C Sameera; Masako Kato; Pradip K Mascharak
Journal:  Inorg Chem       Date:  2017-02-22       Impact factor: 5.165

5.  Efficient photorelease of carbon monoxide from a luminescent tricarbonyl rhenium(I) complex incorporating pyridyl-1,2,4-triazole and phosphine ligands.

Authors:  Ángel D Hernández Mejías; Alexandre Poirot; Meriem Rmili; Nadine Leygue; Mariusz Wolff; Nathalie Saffon-Merceron; Eric Benoist; Suzanne Fery-Forgues
Journal:  Dalton Trans       Date:  2021-02-02       Impact factor: 4.390

6.  Synthesis and crystal structure of tri-carbonyl-chlorido-{1-[(pyridin-2-yl-methyl-idene)amino]-adamantane}rhenium(I).

Authors:  Jorge Jimenez; Indranil Chakraborty; Pradip Mascharak
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2016-08-09

7.  Light-Activated Carbon Monoxide Prodrugs Based on Bipyridyl Dicarbonyl Ruthenium(II) Complexes.

Authors:  Stepan Geri; Tereza Krunclova; Olga Janouskova; Jiri Panek; Martin Hruby; Daniel Hernández-Valdés; Benjamin Probst; Roger A Alberto; Constantin Mamat; Manja Kubeil; Holger Stephan
Journal:  Chemistry       Date:  2020-08-13       Impact factor: 5.236

Review 8.  An Overview of the Potential Therapeutic Applications of CO-Releasing Molecules.

Authors:  Aiten Ismailova; David Kuter; D Scott Bohle; Ian S Butler
Journal:  Bioinorg Chem Appl       Date:  2018-08-12       Impact factor: 7.778

9.  Novel Re(I) tricarbonyl coordination compounds based on 2-pyridyl-1,2,3-triazole derivatives bearing a 4-amino-substituted benzenesulfonamide arm: synthesis, crystal structure, computational studies and inhibitory activity against carbonic anhydrase I, II, and IX isoforms†.

Authors:  Yassine Aimene; Romain Eychenne; Sonia Mallet-Ladeira; Nathalie Saffon; Jean-Yves Winum; Alessio Nocentini; Claudiu T Supuran; Eric Benoist; Achour Seridi
Journal:  J Enzyme Inhib Med Chem       Date:  2019-12       Impact factor: 5.051

10.  Diminished viability of human ovarian cancer cells by antigen-specific delivery of carbon monoxide with a family of photoactivatable antibody-photoCORM conjugates.

Authors:  Brian Kawahara; Lucy Gao; Whitaker Cohn; Julian P Whitelegge; Suvajit Sen; Carla Janzen; Pradip K Mascharak
Journal:  Chem Sci       Date:  2019-11-20       Impact factor: 9.825
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